STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
let-765Protein strawberry notch homolog; Transcriptional activator that functions upstream of the let- 60/Ras and let-23/EGFR signaling pathways to positively regulate lin-3 expression and thereby promote vulval induction. Plays a role in excretory duct development. Plays a role in male tail development. (1866 aa)    
Predicted Functional Partners:
C25F9.4
SNF2_N domain-containing protein.
   
 
 0.713
C25F9.5
Uncharacterized protein.
   
 
 0.713
Y43F8B.14
SNF2_N domain-containing protein.
   
 
 0.713
M04C3.1
SNF2_N domain-containing protein.
   
 
 0.708
C08F8.2
ATP-dependent RNA helicase SUV3 homolog, mitochondrial; ATPase and DNA/RNA helicase able to unwind DNA/DNA, DNA/RNA and RNA/RNA duplexes in the 5'-3' direction.
      
 0.707
F46G11.1
SF4 helicase domain-containing protein.
      
 0.697
F52G3.4
annotation not available
      
 0.696
H20J04.4
Uncharacterized protein; Belongs to the DEAD box helicase family.
   
  
 0.696
F55F8.2
Uncharacterized protein.
   
  
 0.695
F59H6.5
ATP-dependent DNA helicase; Belongs to the helicase family.
      
 0.695
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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