STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ncs-4Neuronal Calcium Sensor family. (224 aa)    
Predicted Functional Partners:
shl-1
BTB domain-containing protein; Belongs to the potassium channel family.
   
 0.889
ncs-5
EF-hand domain-containing protein.
   
 
0.865
ZK1236.1
Translation factor GUF1 homolog, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.
     
 0.808
bath-25
BTB domain-containing protein.
      
 0.806
cal-5
CALmodulin related genes.
   
 
 0.722
efhd-1
EF HanD calcium binding protein.
   
 
 0.700
lin-2
Protein lin-2; May play a structural role in the induction of the vulva. May be required for the localization of signal transduction molecules (such as let-23 receptor) to either the basal membrane domain or the cell junctions.
   
 
 0.692
pifk-1
PhosphoInositide Four Kinase (PI-4 Kinase); Belongs to the PI3/PI4-kinase family.
    
 
 0.644
trp-4
ANK_REP_REGION domain-containing protein; Belongs to the transient receptor (TC 1.A.4) family.
    
 
 0.561
ncx-3
Na/Ca eXchangers; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.
      
 0.537
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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