STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
frpr-6G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (349 aa)    
Predicted Functional Partners:
dmsr-13
G_PROTEIN_RECEP_F1_2 domain-containing protein.
  
   
 0.750
dmsr-9
G_PROTEIN_RECEP_F1_2 domain-containing protein.
   
  
 0.703
dmsr-12
G_PROTEIN_RECEP_F1_2 domain-containing protein.
      
 0.697
dmsr-15
G_PROTEIN_RECEP_F1_2 domain-containing protein.
      
 0.697
dmsr-16
G_PROTEIN_RECEP_F1_2 domain-containing protein.
      
 0.697
dmsr-14
G_PROTEIN_RECEP_F1_2 domain-containing protein.
      
 0.660
dmsr-10
G_PROTEIN_RECEP_F1_2 domain-containing protein.
      
 0.660
dmsr-7
G_PROTEIN_RECEP_F1_2 domain-containing protein.
   
  
 0.600
gar-2
Muscarinic acetylcholine receptor gar-2; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover (By similarity). Regulates the activity of ventral cord motor neurons. Couples to the G(o) alpha G-protein subunit goa-1 to negatively regulate cholinergic receptor activity in the presence of high levels of the neurotransmitter acetylcholine in ventral cord motor neurons. As acetylcholin [...]
  
  
 0.595
srx-90
G_PROTEIN_RECEP_F1_2 domain-containing protein.
      
 0.581
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.