STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hint-1Histidine triad nucleotide-binding protein 1. (130 aa)    
Predicted Functional Partners:
C44B7.12
Adenosine deaminase-like protein; Catalyzes the hydrolysis of the free cytosolic methylated adenosine nucleotide N(6)-methyl-AMP (N6-mAMP) to produce inositol monophosphate (IMP) and methylamine. Is required for the catabolism of cytosolic N6-mAMP, which is derived from the degradation of mRNA containing N6-methylated adenine (m6A); Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
  
 
 0.839
C52A10.2
Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family.
   
  
 0.758
rpl-38
60S ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family.
   
  
 0.725
cal-5
CALmodulin related genes.
   
  
 0.718
mrp-6
Uncharacterized protein.
     
 0.672
rps-18
Ribosomal Protein, Small subunit; Belongs to the universal ribosomal protein uS13 family.
  
    0.646
ndx-4
Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]; Asymmetrically hydrolyzes Ap4A to yield AMP and ATP.
  
 
 0.613
rps-15
40S ribosomal protein S15; Negatively regulates lifespan.
   
  
 0.607
snr-6
Probable small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.
   
  
 0.593
rpl-27
60S ribosomal protein L27; Component of the large ribosomal subunit.
   
 
 0.586
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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