STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rde-2Uncharacterized protein. (578 aa)    
Predicted Functional Partners:
mut-7
Exonuclease mut-7; Represses the transposition of Tc1, Tc3, Tc4, and Tc5, perhaps by degrading transposon-specific messages. Also affects sperm development, sensitivity to RNAi of mainly germline expressed genes, silencing of some germline transgenes, X chromosome loss, and is required for cosuppression (functional silencing of chromosomal loci induced by transgenes) and for silencing induced by antisense RNA oligomers.
   
 
 0.957
mut-16
MUTator.
   
 
 0.878
mut-14
MUTator; Belongs to the DEAD box helicase family.
   
  
 0.865
rde-4
RNA interference promoting factor.
   
  
 0.864
smut-1
Synthetic MUTator.
   
 
 0.810
mut-2
NTP_transf_2 domain-containing protein.
   
  
 0.792
rde-1
RNA interference promoting factor RDE-1.
   
  
 0.778
ekl-5
Uncharacterized protein.
   
  
 0.777
mut-15
MUTator.
   
  
 0.771
rrf-1
RNA-dependent RNA polymerase Family.
   
  
 0.708
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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