STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ceh-60Homeobox domain-containing protein. (360 aa)    
Predicted Functional Partners:
unc-62
Homeobox protein unc-62; Acts redundantly with ceh-20 and ceh-40 to perform overlapping roles during embryogenesis. Required for postembryonic development of the ectoderm, including the Q, V and P cell lineages, playing a crucial role in ensuring that these cells and their descendants undergo their invariant patterns of cell division, migration, fusion and morphogenesis. Has a role in the mig-13 pathway to promote anterior migration of neuroblasts in the Q lineage. Required for multiple roles in regulating vulva development. Belongs to the TALE/MEIS homeobox family.
  
 
0.956
vrp-1
Vitellogenin Regulating Protein.
   
  
 0.818
php-3
Homeobox domain-containing protein.
    
 
 0.798
pqm-1
C2H2-type domain-containing protein.
   
 
 0.779
nob-1
Homeobox domain-containing protein.
    
 
 0.734
lrp-2
Low-density lipoprotein RecePtor related.
   
  
 0.669
egrh-2
EGR (Early Growth factor Response factor) Homolog.
      
 0.660
psa-3
Meis_PKNOX_N domain-containing protein.
    
 
 0.645
egl-5
Homeobox protein egl-5; Essential for the determination of specific neurons.
    
 
 0.613
ceh-13
Homeobox protein ceh-13.
    
 
 0.598
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.