STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cut-3ZP domain-containing protein. (389 aa)    
Predicted Functional Partners:
col-74
Col_cuticle_N domain-containing protein.
   
   0.766
F49C12.7
CHK domain-containing protein.
      
 0.758
ZK593.3
Uncharacterized protein.
      
 0.758
cutl-28
CUTiclin-Like.
   
 
 0.716
Y4C6B.2
Aa_trans domain-containing protein.
    
 
 0.710
ile-1
L-type lectin-like domain-containing protein.
      
 0.699
W02D9.10
Uncharacterized protein.
      
 0.698
dpf-6
Dipeptidyl peptidase family member 6; Removes N-terminal dipeptides sequentially from polypeptides (By similarity). Essential for control of distal tip cell migration.
    
 
 0.631
col-165
Col_cuticle_N domain-containing protein.
   
   0.625
smc-4
Structural maintenance of chromosomes protein 4; Central component of the condensin I complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin I complex introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases. Converts nicked DNA into positive knotted forms in the presence of type II topoisomerases (By similarity). Also a central component of the condensin II complex, a complex that seems to play a role in prophase chromosome condensation. Both the condensin complex I and II play a role in [...]
    
 
 0.538
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (20%) [HD]