STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F22D6.2Uncharacterized protein. (189 aa)    
Predicted Functional Partners:
rabn-5
FYVE-type domain-containing protein.
   
 
 0.743
srp-1
Serine or cysteine protease inhibitor; Belongs to the serpin family.
   
  
 0.664
T10B11.6
Uncharacterized protein.
   
  
 0.663
W04C9.4
Uncharacterized protein.
      
 0.660
F35H12.1
SCHIP-1 domain-containing protein.
      
 0.621
lgg-2
Protein lgg-2; Ubiquitin-like modifier involved in the formation of autophagosomal vacuoles (autophagosomes). When lipidated mediates tethering between adjacent membranes and stimulates membrane fusion. Less effective at promoting membrane fusion than lgg-1. Acts upstream of the autophagy protein epg-5 in the aggrephagy pathway, which is the macroautophagic degradation of ubiquitinated protein aggregates, and preferentially interacts with autophagy proteins and substrates containing LIR motifs to mediate autophagosome formation and protein aggregate degradation. In particular binds to [...]
   
  
 0.556
rab-21
RAB family.
   
 
 0.547
atgp-2
Aamy domain-containing protein.
    
 
 0.462
atgp-1
Aamy domain-containing protein.
    
 
 0.462
R01B10.3
SLC3A2_N domain-containing protein.
    
 
 0.462
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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