STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bgnt-1.2B3GNT1, Beta-1,3-N-acetylGucosamiNylTransferase 1, homolog. (406 aa)    
Predicted Functional Partners:
T07A5.1
Uncharacterized protein T07A5.1.
      
 0.912
lge-1
Glycosyltransferase-like protein LARGE; Probable glycosyltransferase; Belongs to the glycosyltransferase 8 family.
      
 0.905
sqv-2
Beta-1,3-galactosyltransferase sqv-2; Beta-1,3-galactosyltransferase that transfers galactose from UDP-galactose to substrates with a terminal beta-linked galactose residue. Required for vulval morphogenesis and zygotic cytokinesis, suggesting that glycosaminoglycans play a central role in vulval morphogenesis.
   
  
 0.904
M70.4
Uncharacterized protein.
      
 0.867
sqv-6
Xylosyltransferase sqv-6; Catalyzes the first step in biosynthesis of glycosaminoglycan. Transfers D-xylose from UDP-D-xylose to specific serine residues of the core protein. Initial enzyme in the biosynthesis of chondroitin sulfate and dermatan sulfate proteoglycans in fibroblasts and chondrocytes. Required for vulval morphogenesis and zygotic cytokinesis, suggesting that glycosaminoglycans play a central role in vulval morphogenesis.
      
 0.852
tag-335
Mannose-1-phosphate guanyltransferase beta; Belongs to the transferase hexapeptide repeat family.
      
 0.707
dpm-1
Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins.
      
 0.683
bgnt-1.3
B3GNT1, Beta-1,3-N-acetylGucosamiNylTransferase 1, homolog.
   
   
0.432
F36F12.1
Glycosyltransferase family 92 protein; Belongs to the glycosyltransferase 92 family.
   
    0.412
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.