STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F23B12.1Serine/threonine-protein phosphatase. (329 aa)    
Predicted Functional Partners:
Y47G6A.26
Uncharacterized protein.
   
 
 0.654
C06A8.6
LRRcap domain-containing protein.
 
 
 
 0.649
C34D4.2
Serine/threonine-protein phosphatase.
  
   
0.619
C36H8.1
Major sperm protein; Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.
   
   0.602
K10H10.7
Uncharacterized protein.
   
 
 0.602
T02E1.7
Uncharacterized protein T02E1.7; Belongs to the SURF4 family.
   
   0.596
wht-5
ABC transporter domain-containing protein.
   
   0.583
C25A8.5
Tyrosine-protein kinase.
   
   0.577
BE10.1
Uncharacterized protein.
   
    0.572
his-70
Histone H3.3-like type 1; Putative variant histone H3 which may replace conventional H3 in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity).
   
   0.570
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.