STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fntb-1Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding. (401 aa)    
Predicted Functional Partners:
fnta-1
FarNesylTransferase, Alpha subunit.
   
 0.999
fce-2
CAAX prenyl protease 2 homolog; Proteolytically removes the C-terminal three residues of farnesylated and geranylated proteins; Belongs to the peptidase U48 family.
   
 0.974
fce-1
CAAX prenyl protease 1 homolog; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.
   
 
 0.966
fdps-1
Farnesyl DiPhosphate Synthetase; Belongs to the FPP/GGPP synthase family.
   
 0.964
T01G1.4
Alkyl transferase; Belongs to the UPP synthase family.
     
 0.955
coq-1
COenzyme Q (Ubiquinone) biosynthesis; Belongs to the FPP/GGPP synthase family.
    
 0.951
F23B12.7
Uncharacterized protein F23B12.7; Belongs to the CBF/MAK21 family.
 
 
  
 0.876
let-60
Ras protein let-60; The level of let-60 controls the switch between vulval and hypodermal cell fates during C.elegans vulval induction. May stimulate the guanine nucleotide exchange factor (GEF) activity of rap-1. Belongs to the small GTPase superfamily. Ras family.
    
 0.812
chaf-1
CHromatin Assembly Factor.
   
  
 0.761
gpc-1
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
     
  0.750
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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