STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F23B2.10RING-type domain-containing protein. (393 aa)    
Predicted Functional Partners:
srx-29
7TM_GPCR_Srx domain-containing protein.
      
 0.850
sru-6
Serpentine Receptor, class U.
      
 0.808
tax-6
Serine/threonine-protein phosphatase 2B catalytic subunit; Calcium-dependent, calmodulin-stimulated protein phosphatase. Dephosphorylates arrd-17. Dephosphorylates daf-16 at 'Ser-319' which regulates daf-16 nuclear translocation. Dephosphorylates calcium permeable cation channel pkd-2 at 'Ser-534'. Regulates male mating behavior including response to hermaphrodite contact and vulva location and localization of pkd-2 to neuronal cilium. Negatively regulates several sensory behaviors including thermotaxis in ADF neurons, osmosensation in ASH neurons, olfaction adaptation in AWC neurons a [...]
      
 0.550
pals-38
Protein containing ALS2cr12 (ALS2CR12) signature.
   
    0.402
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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