STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pef-1Serine/threonine-protein phosphatase with EF-hands pef-1; Probably acts as a protein phosphatase. (707 aa)    
Predicted Functional Partners:
kvs-1
Uncharacterized protein; Belongs to the potassium channel family.
   
 
 0.717
mps-1
MiRP K channel accessory Subunit.
   
  
 0.699
mgl-2
G_PROTEIN_RECEP_F3_4 domain-containing protein.
   
  
 0.676
rbc-2
RaBConnectin related.
    
 
 0.596
kin-29
Serine/threonine-protein kinase kin-29; Regulates chemoreceptor expression by phosphorylating the hda-4 class II histone deacetylase (HDAC) and inhibiting the gene repression functions of hda-4 and the mef-2 transcription factor, enabling the correct sensing and transduction of food signals. Role in determining body size, the dauer decision and serotonin-mediated egg laying. May modulate the Sma/Mab pathway and regulates development in the later larval stages.
   
 
 0.558
rbm-12
RNA Binding Motif protein homolog.
      
 0.541
Y55D5A.3
N-acylethanolamine-hydrolyzing acid amidase subunit alpha; Degrades bioactive fatty acid amides, such as N- palmitoylethanolamine, to ethanolamine and free fatty acids. Belongs to the acid ceramidase family.
 
 
 
 0.536
che-2
CHE-2 protein.
   
 
 0.508
tag-307
ApaG domain-containing protein.
  
  
 0.494
iglr-3
Ig-like domain-containing protein.
   
 
 0.490
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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