node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
acc-1 | acr-16 | F58G6.4b.1 | F25G6.3.1 | Acetylcholine-gated chloride channel subunit acc-1; Acetylcholine-gated chloride channel subunit. Forms functional homopentameric (in vitro) and functional heteropentameric ion channels with acc-3 and acc-4 ion channel subunits. Currents in channels are triggered in response to acetylcholine, but not in response to GABA, glutamate, glycine, histamine or dopamine. | Acetylcholine receptor subunit alpha-type acr-16; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane (By similarity). A subunit of the levamisole-insensitive nicotinic receptor. | 0.624 |
acc-1 | lgc-25 | F58G6.4b.1 | R03E1.3.1 | Acetylcholine-gated chloride channel subunit acc-1; Acetylcholine-gated chloride channel subunit. Forms functional homopentameric (in vitro) and functional heteropentameric ion channels with acc-3 and acc-4 ion channel subunits. Currents in channels are triggered in response to acetylcholine, but not in response to GABA, glutamate, glycine, histamine or dopamine. | Neur_chan_LBD domain-containing protein. | 0.642 |
acc-1 | lgc-26 | F58G6.4b.1 | Y58G8A.1.1 | Acetylcholine-gated chloride channel subunit acc-1; Acetylcholine-gated chloride channel subunit. Forms functional homopentameric (in vitro) and functional heteropentameric ion channels with acc-3 and acc-4 ion channel subunits. Currents in channels are triggered in response to acetylcholine, but not in response to GABA, glutamate, glycine, histamine or dopamine. | Neur_chan_LBD domain-containing protein. | 0.484 |
ace-3 | acr-16 | Y48B6A.8.1 | F25G6.3.1 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Acetylcholine receptor subunit alpha-type acr-16; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane (By similarity). A subunit of the levamisole-insensitive nicotinic receptor. | 0.684 |
ace-3 | ric-3 | Y48B6A.8.1 | T14A8.1.1 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Resistance to inhibitors of cholinesterase protein 3; Required for maturation and cell surface expression of acetylcholine receptors; Belongs to the ric-3 family. | 0.825 |
ace-3 | unc-17 | Y48B6A.8.1 | ZC416.8a.1 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Vesicular acetylcholine transporter unc-17; Involved in acetylcholine transport into synaptic vesicles. Belongs to the major facilitator superfamily. Vesicular transporter family. | 0.736 |
ace-3 | unc-50 | Y48B6A.8.1 | T07A5.2.1 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | Protein unc-50; Required for cell surface expression of acetylcholine receptors in body-wall muscles. | 0.468 |
acr-16 | acc-1 | F25G6.3.1 | F58G6.4b.1 | Acetylcholine receptor subunit alpha-type acr-16; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane (By similarity). A subunit of the levamisole-insensitive nicotinic receptor. | Acetylcholine-gated chloride channel subunit acc-1; Acetylcholine-gated chloride channel subunit. Forms functional homopentameric (in vitro) and functional heteropentameric ion channels with acc-3 and acc-4 ion channel subunits. Currents in channels are triggered in response to acetylcholine, but not in response to GABA, glutamate, glycine, histamine or dopamine. | 0.624 |
acr-16 | ace-3 | F25G6.3.1 | Y48B6A.8.1 | Acetylcholine receptor subunit alpha-type acr-16; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane (By similarity). A subunit of the levamisole-insensitive nicotinic receptor. | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. | 0.684 |
acr-16 | dsh-1 | F25G6.3.1 | C34F11.9e.1 | Acetylcholine receptor subunit alpha-type acr-16; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane (By similarity). A subunit of the levamisole-insensitive nicotinic receptor. | DiSHevelled related. | 0.614 |
acr-16 | gar-3 | F25G6.3.1 | Y40H4A.1b.1 | Acetylcholine receptor subunit alpha-type acr-16; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane (By similarity). A subunit of the levamisole-insensitive nicotinic receptor. | Muscarinic acetylcholine receptor gar-3; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover (By similarity). Enhances the release of the neurotransmitter acetlycholine in cholinergic motor neurons, which in turn positively feeds back to depolarize body wall muscles and allows for the maintenance of normal body posture and locomotion. | 0.757 |
acr-16 | glc-4 | F25G6.3.1 | C27H5.8.1 | Acetylcholine receptor subunit alpha-type acr-16; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane (By similarity). A subunit of the levamisole-insensitive nicotinic receptor. | Glutamate-gated ChLoride channel; Belongs to the ligand-gated ion channel (TC 1.A.9) family. | 0.634 |
acr-16 | lgc-25 | F25G6.3.1 | R03E1.3.1 | Acetylcholine receptor subunit alpha-type acr-16; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane (By similarity). A subunit of the levamisole-insensitive nicotinic receptor. | Neur_chan_LBD domain-containing protein. | 0.575 |
acr-16 | lgc-26 | F25G6.3.1 | Y58G8A.1.1 | Acetylcholine receptor subunit alpha-type acr-16; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane (By similarity). A subunit of the levamisole-insensitive nicotinic receptor. | Neur_chan_LBD domain-containing protein. | 0.626 |
acr-16 | ric-3 | F25G6.3.1 | T14A8.1.1 | Acetylcholine receptor subunit alpha-type acr-16; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane (By similarity). A subunit of the levamisole-insensitive nicotinic receptor. | Resistance to inhibitors of cholinesterase protein 3; Required for maturation and cell surface expression of acetylcholine receptors; Belongs to the ric-3 family. | 0.943 |
acr-16 | unc-17 | F25G6.3.1 | ZC416.8a.1 | Acetylcholine receptor subunit alpha-type acr-16; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane (By similarity). A subunit of the levamisole-insensitive nicotinic receptor. | Vesicular acetylcholine transporter unc-17; Involved in acetylcholine transport into synaptic vesicles. Belongs to the major facilitator superfamily. Vesicular transporter family. | 0.658 |
acr-16 | unc-50 | F25G6.3.1 | T07A5.2.1 | Acetylcholine receptor subunit alpha-type acr-16; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane (By similarity). A subunit of the levamisole-insensitive nicotinic receptor. | Protein unc-50; Required for cell surface expression of acetylcholine receptors in body-wall muscles. | 0.858 |
dsh-1 | acr-16 | C34F11.9e.1 | F25G6.3.1 | DiSHevelled related. | Acetylcholine receptor subunit alpha-type acr-16; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane (By similarity). A subunit of the levamisole-insensitive nicotinic receptor. | 0.614 |
dsh-1 | gar-3 | C34F11.9e.1 | Y40H4A.1b.1 | DiSHevelled related. | Muscarinic acetylcholine receptor gar-3; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover (By similarity). Enhances the release of the neurotransmitter acetlycholine in cholinergic motor neurons, which in turn positively feeds back to depolarize body wall muscles and allows for the maintenance of normal body posture and locomotion. | 0.406 |
gar-3 | acr-16 | Y40H4A.1b.1 | F25G6.3.1 | Muscarinic acetylcholine receptor gar-3; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover (By similarity). Enhances the release of the neurotransmitter acetlycholine in cholinergic motor neurons, which in turn positively feeds back to depolarize body wall muscles and allows for the maintenance of normal body posture and locomotion. | Acetylcholine receptor subunit alpha-type acr-16; After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane (By similarity). A subunit of the levamisole-insensitive nicotinic receptor. | 0.757 |