node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
W07E11.1 | alh-13 | W07E11.1b.1 | T22H6.2b.1 | Glutamine amidotransferase type-2 domain-containing protein. | Probable delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.989 |
W07E11.1 | asns-1 | W07E11.1b.1 | F25G6.6.1 | Glutamine amidotransferase type-2 domain-containing protein. | Glutamine amidotransferase type-2 domain-containing protein. | 0.873 |
W07E11.1 | asns-2 | W07E11.1b.1 | M02D8.4a.1 | Glutamine amidotransferase type-2 domain-containing protein. | Glutamine amidotransferase type-2 domain-containing protein. | 0.874 |
W07E11.1 | gdh-1 | W07E11.1b.1 | ZK829.4.1 | Glutamine amidotransferase type-2 domain-containing protein. | Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.999 |
W07E11.1 | got-1.2 | W07E11.1b.1 | T01C8.5.1 | Glutamine amidotransferase type-2 domain-containing protein. | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the central nervous system. | 0.641 |
W07E11.1 | got-2.1 | W07E11.1b.1 | C44E4.3.1 | Glutamine amidotransferase type-2 domain-containing protein. | Aspartate aminotransferase. | 0.446 |
W07E11.1 | got-2.2 | W07E11.1b.1 | C14F11.1a.2 | Glutamine amidotransferase type-2 domain-containing protein. | Aspartate aminotransferase. | 0.596 |
W07E11.1 | pyr-1 | W07E11.1b.1 | D2085.1.1 | Glutamine amidotransferase type-2 domain-containing protein. | Glutamine-dependent carbamoyl-phosphate synthase; This protein is a 'fusion' protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) (By similarity). Involved in the elongation of the pharyngeal isthmus during development, probably by providing precursors of UDP- sugars required for heparan sulfate proteoglycan biosynthesis. Regulates the organization of the actin and intermediate filaments cytoskeleton in the pharyngeal muscles ; In the central section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily. | 0.995 |
W07E11.1 | unc-25 | W07E11.1b.1 | Y37D8A.23a.1 | Glutamine amidotransferase type-2 domain-containing protein. | Glutamic acid decarboxylase. | 0.913 |
adss-1 | alh-13 | C37H5.6a.1 | T22H6.2b.1 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. | Probable delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.838 |
adss-1 | asns-1 | C37H5.6a.1 | F25G6.6.1 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. | Glutamine amidotransferase type-2 domain-containing protein. | 0.942 |
adss-1 | asns-2 | C37H5.6a.1 | M02D8.4a.1 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. | Glutamine amidotransferase type-2 domain-containing protein. | 0.942 |
adss-1 | gdh-1 | C37H5.6a.1 | ZK829.4.1 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. | Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.409 |
adss-1 | got-1.2 | C37H5.6a.1 | T01C8.5.1 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. | Aspartate aminotransferase, cytoplasmic; Biosynthesis of L-glutamate from L-aspartate. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the central nervous system. | 0.937 |
adss-1 | got-2.1 | C37H5.6a.1 | C44E4.3.1 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. | Aspartate aminotransferase. | 0.936 |
adss-1 | got-2.2 | C37H5.6a.1 | C14F11.1a.2 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. | Aspartate aminotransferase. | 0.951 |
adss-1 | pyr-1 | C37H5.6a.1 | D2085.1.1 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. | Glutamine-dependent carbamoyl-phosphate synthase; This protein is a 'fusion' protein encoding four enzymatic activities of the pyrimidine pathway (GATase, CPSase, ATCase and DHOase) (By similarity). Involved in the elongation of the pharyngeal isthmus during development, probably by providing precursors of UDP- sugars required for heparan sulfate proteoglycan biosynthesis. Regulates the organization of the actin and intermediate filaments cytoskeleton in the pharyngeal muscles ; In the central section; belongs to the metallo-dependent hydrolases superfamily. DHOase family. CAD subfamily. | 0.985 |
adss-1 | unc-25 | C37H5.6a.1 | Y37D8A.23a.1 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. | Glutamic acid decarboxylase. | 0.813 |
alh-13 | W07E11.1 | T22H6.2b.1 | W07E11.1b.1 | Probable delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Glutamine amidotransferase type-2 domain-containing protein. | 0.989 |
alh-13 | adss-1 | T22H6.2b.1 | C37H5.6a.1 | Probable delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. | 0.838 |