STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F25H2.4MPN domain-containing protein. (196 aa)    
Predicted Functional Partners:
emc-2
TPR_REGION domain-containing protein.
   
 0.994
emc-3
ER membrane protein complex subunit 3.
   
 0.974
perm-3
ER membrane protein complex subunit 4; Belongs to the EMC4 family.
   
 0.972
emc-1
EMC1_C domain-containing protein.
   
 0.970
C35D10.1
ER membrane protein complex subunit 7 homolog.
   
 0.946
emc-5
EMC Endoplasmic Membrane protein Complex (Yeast EMC) homolog.
   
 0.940
emc-6
EMC Endoplasmic Membrane protein Complex (Yeast EMC) homolog.
   
 0.940
Y43F8C.7
Uncharacterized protein.
   
 0.937
F10C2.4
DNA polymerase delta catalytic subunit; Possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single stranded DNA in the 3'- to 5'-direction. Required with its accessory proteins (proliferating cell nuclear antigen (PCNA) and replication factor C (RFC) or activator 1) for leading strand synthesis. Also involved in completing Okazaki fragments initiated by the DNA polymerase alpha/primase complex (By similarity).
   
  
 0.835
npp-19
Nucleoporin NUP35; Functions as a component of the nuclear pore complex (NPC) (By similarity). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors (By similarity). Required for the proper organization of chromosomes on the mitotic spindle during anaphase.
   
  
 0.691
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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