STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bed-3Zinc finger BED domain-containing protein 3; Probable transcription factor involved in vulval organogenesis. During vulval development, may play a role in the regulation of cell cycle regulators such as cul-1. Plays a role in larval molting. (599 aa)    
Predicted Functional Partners:
col-124
Col_cuticle_N domain-containing protein.
   
  
 0.809
T09D3.8
DUF281 domain-containing protein.
      
 0.806
blmp-1
B lymphocyte-induced maturation protein 1 homolog; Transcription factor which binds to enhancer elements in the promoter region of genes. Regulates the expression of the transcription factor bed-3 to control vulval development. Promotes terminal differentiation in the hypodermis and is involved in regulation of gonadal outgrowth and entry into the dauer stage. Regulates the timing of dorsalward migration of the distal tip cells of the hermaphrodite gonad by inhibiting precocious unc-5 and lin-29 expression which in turn prevents early dorsalward turning. Plays a role in male tail tip m [...]
   
  
 0.721
B0238.11
Uncharacterized protein.
      
 0.695
ztf-17
Zinc finger transcription factor family protein 17.
      
 0.660
vab-23
Uncharacterized protein.
      
 0.617
nas-10
Zinc metalloproteinase nas-10; Metalloprotease.
   
  
 0.590
tbx-39
Putative T-box protein 39.
      
 0.588
cog-1
Homeobox domain-containing protein.
      
 0.585
suro-1
Putative carboxypeptidase suro-1; May play a role in processing or organization of cuticle collagen proteins, including rol-6 and col-19.
   
  
 0.569
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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