fkh-7 protein (Caenorhabditis elegans) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

fkh-7

Fork-head domain-containing protein. (778 aa)

Predicted Functional Partners:

fkh-5

0.838

fkh-3

0.775

fkh-4

0.737

hil-1

0.703

bath-15

0.702

mak-1

0.698

rnt-1

0.643

bro-1

0.584

pros-1

0.555

vab-3

0.539

Your Current Organism:

Caenorhabditis elegans

NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
bath-15	fkh-7	C08C3.2b.1	F26D12.1a.1	BTB and MATH domain-containing protein 15; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.	Fork-head domain-containing protein.	0.702
bath-15	mak-1	C08C3.2b.1	K08F8.1a.2	BTB and MATH domain-containing protein 15; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.	MAP kinase-activated protein kinase mak-1; Serine/threonine-protein kinase which may play a role in body wall muscle contraction. May phosphorylate unc-22/twitchin. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.	0.660
bro-1	fkh-7	F56A3.5.1	F26D12.1a.1	BROther (Drosophila tx factor partner) homolog.	Fork-head domain-containing protein.	0.584
bro-1	rnt-1	F56A3.5.1	B0414.2.2	BROther (Drosophila tx factor partner) homolog.	Runt domain-containing protein.	0.999
fkh-3	fkh-4	C29F7.4a.1	C29F7.5.1	Fork-head domain-containing protein.	Fork-head domain-containing protein.	0.955
fkh-3	fkh-5	C29F7.4a.1	F26A1.2.1	Fork-head domain-containing protein.	Putative forkhead-related transcription factor fkh-5.	0.406
fkh-3	fkh-7	C29F7.4a.1	F26D12.1a.1	Fork-head domain-containing protein.	Fork-head domain-containing protein.	0.775
fkh-4	fkh-3	C29F7.5.1	C29F7.4a.1	Fork-head domain-containing protein.	Fork-head domain-containing protein.	0.955
fkh-4	fkh-5	C29F7.5.1	F26A1.2.1	Fork-head domain-containing protein.	Putative forkhead-related transcription factor fkh-5.	0.460
fkh-4	fkh-7	C29F7.5.1	F26D12.1a.1	Fork-head domain-containing protein.	Fork-head domain-containing protein.	0.737
fkh-5	fkh-3	F26A1.2.1	C29F7.4a.1	Putative forkhead-related transcription factor fkh-5.	Fork-head domain-containing protein.	0.406
fkh-5	fkh-4	F26A1.2.1	C29F7.5.1	Putative forkhead-related transcription factor fkh-5.	Fork-head domain-containing protein.	0.460
fkh-5	fkh-7	F26A1.2.1	F26D12.1a.1	Putative forkhead-related transcription factor fkh-5.	Fork-head domain-containing protein.	0.838
fkh-7	bath-15	F26D12.1a.1	C08C3.2b.1	Fork-head domain-containing protein.	BTB and MATH domain-containing protein 15; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.	0.702
fkh-7	bro-1	F26D12.1a.1	F56A3.5.1	Fork-head domain-containing protein.	BROther (Drosophila tx factor partner) homolog.	0.584
fkh-7	fkh-3	F26D12.1a.1	C29F7.4a.1	Fork-head domain-containing protein.	Fork-head domain-containing protein.	0.775
fkh-7	fkh-4	F26D12.1a.1	C29F7.5.1	Fork-head domain-containing protein.	Fork-head domain-containing protein.	0.737
fkh-7	fkh-5	F26D12.1a.1	F26A1.2.1	Fork-head domain-containing protein.	Putative forkhead-related transcription factor fkh-5.	0.838
fkh-7	hil-1	F26D12.1a.1	C30G7.1.1	Fork-head domain-containing protein.	Histone H1.X.	0.703
fkh-7	mak-1	F26D12.1a.1	K08F8.1a.2	Fork-head domain-containing protein.	MAP kinase-activated protein kinase mak-1; Serine/threonine-protein kinase which may play a role in body wall muscle contraction. May phosphorylate unc-22/twitchin. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.	0.698