STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
syp-1Synaptonemal complex protein SYP-1. (489 aa)    
Predicted Functional Partners:
him-3
HORMA domain-containing protein.
   
  
 0.799
syp-3
Uncharacterized protein.
   
 
 0.765
zhp-2
RING-type domain-containing protein.
   
  
 0.758
syp-2
Uncharacterized protein.
   
 
 0.754
cosa-1
CrossOver Site Associated.
   
 
 0.725
zhp-4
Zip (Yeast meiotic zipper) Homologous Protein.
   
 
 0.608
zhp-1
Zip (Yeast meiotic zipper) Homologous Protein.
   
  
 0.550
coh-3
Rad21_Rec8 domain-containing protein.
   
  
 0.533
golg-2
GOLGi associated coiled-coil protein homolog.
   
 
 0.509
fubl-4
FUBp (FUBP) Like.
   
    0.507
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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