Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Y106G6E.4 | rom-1 | Y106G6E.4.1 | F26F4.3.1 | Probable 5-formyltetrahydrofolate cyclo-ligase; Contributes to tetrahydrofolate metabolism. Helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids. Catalyzes the irreversible conversion of 5- formyltetrahydrofolate (5-CHO-H(4)PteGlu) to yield 5,10- methenyltetrahydrofolate (By similarity). | Rhomboid-related protein 1; Serine protease which activates lin-3 isoform a in the proximal vulva precursor cells (VPC) during vulva development to transmit the inductive anchor cell signal to the distal VPCs. | 0.502 |
| Y106G6E.4 | rom-3 | Y106G6E.4.1 | Y116A8C.14a.1 | Probable 5-formyltetrahydrofolate cyclo-ligase; Contributes to tetrahydrofolate metabolism. Helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids. Catalyzes the irreversible conversion of 5- formyltetrahydrofolate (5-CHO-H(4)PteGlu) to yield 5,10- methenyltetrahydrofolate (By similarity). | Rhomboid domain-containing protein. | 0.502 |
| Y106G6E.4 | rom-4 | Y106G6E.4.1 | Y116A8C.16c.1 | Probable 5-formyltetrahydrofolate cyclo-ligase; Contributes to tetrahydrofolate metabolism. Helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids. Catalyzes the irreversible conversion of 5- formyltetrahydrofolate (5-CHO-H(4)PteGlu) to yield 5,10- methenyltetrahydrofolate (By similarity). | Rhomboid domain-containing protein. | 0.502 |
| Y106G6E.4 | rom-5 | Y106G6E.4.1 | Y54E10A.14.1 | Probable 5-formyltetrahydrofolate cyclo-ligase; Contributes to tetrahydrofolate metabolism. Helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids. Catalyzes the irreversible conversion of 5- formyltetrahydrofolate (5-CHO-H(4)PteGlu) to yield 5,10- methenyltetrahydrofolate (By similarity). | Rhomboid domain-containing protein. | 0.502 |
| eat-3 | rom-1 | D2013.5.1 | F26F4.3.1 | Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. | Rhomboid-related protein 1; Serine protease which activates lin-3 isoform a in the proximal vulva precursor cells (VPC) during vulva development to transmit the inductive anchor cell signal to the distal VPCs. | 0.450 |
| eat-3 | rom-3 | D2013.5.1 | Y116A8C.14a.1 | Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. | Rhomboid domain-containing protein. | 0.427 |
| eat-3 | rom-4 | D2013.5.1 | Y116A8C.16c.1 | Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. | Rhomboid domain-containing protein. | 0.437 |
| eat-3 | rom-5 | D2013.5.1 | Y54E10A.14.1 | Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. | Rhomboid domain-containing protein. | 0.670 |
| fce-1 | gap-2 | C04F12.10.1 | ZK899.8c.1 | CAAX prenyl protease 1 homolog; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. | Ras GTPase-activating protein gap-2; GTPase-activating protein, which acts as a negative regulator for the member of the Ras family let-60. Probably decreases the signaling activity of Ras by stimulating its intrinsic GTPase activity, thereby lowering the levels of GTP-bound, active Ras. The different isoforms may play a distinct role in specific tissues. | 0.467 |
| fce-1 | pqn-70 | C04F12.10.1 | T19B10.4a.1 | CAAX prenyl protease 1 homolog; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. | Prion-like-(Q/N-rich)-domain-bearing protein. | 0.696 |
| fce-1 | rom-1 | C04F12.10.1 | F26F4.3.1 | CAAX prenyl protease 1 homolog; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. | Rhomboid-related protein 1; Serine protease which activates lin-3 isoform a in the proximal vulva precursor cells (VPC) during vulva development to transmit the inductive anchor cell signal to the distal VPCs. | 0.651 |
| gap-2 | fce-1 | ZK899.8c.1 | C04F12.10.1 | Ras GTPase-activating protein gap-2; GTPase-activating protein, which acts as a negative regulator for the member of the Ras family let-60. Probably decreases the signaling activity of Ras by stimulating its intrinsic GTPase activity, thereby lowering the levels of GTP-bound, active Ras. The different isoforms may play a distinct role in specific tissues. | CAAX prenyl protease 1 homolog; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. | 0.467 |
| gap-2 | let-23 | ZK899.8c.1 | ZK1067.1d.1 | Ras GTPase-activating protein gap-2; GTPase-activating protein, which acts as a negative regulator for the member of the Ras family let-60. Probably decreases the signaling activity of Ras by stimulating its intrinsic GTPase activity, thereby lowering the levels of GTP-bound, active Ras. The different isoforms may play a distinct role in specific tissues. | Receptor tyrosine-protein kinase let-23; Tyrosine-protein kinase receptor which, upon binding ligand lin-3, activates 2 signaling cascades: the let-60/Ras and MAP kinase signaling pathway and the let-60-independent phospholipase C-mediated Ca(2+) signaling pathway. Each pathway regulates distinct functions. By activating let-60/Ras, regulates larval development, induction of vulva cell precursors during vulva development, male spicule formation and posterior development of the epidermis. Probably by activating phospholipase plc-3 and inositol 1,4,5-trisphosphate receptor itr-1 signalin [...] | 0.639 |
| gap-2 | pqn-70 | ZK899.8c.1 | T19B10.4a.1 | Ras GTPase-activating protein gap-2; GTPase-activating protein, which acts as a negative regulator for the member of the Ras family let-60. Probably decreases the signaling activity of Ras by stimulating its intrinsic GTPase activity, thereby lowering the levels of GTP-bound, active Ras. The different isoforms may play a distinct role in specific tissues. | Prion-like-(Q/N-rich)-domain-bearing protein. | 0.520 |
| gap-2 | rom-1 | ZK899.8c.1 | F26F4.3.1 | Ras GTPase-activating protein gap-2; GTPase-activating protein, which acts as a negative regulator for the member of the Ras family let-60. Probably decreases the signaling activity of Ras by stimulating its intrinsic GTPase activity, thereby lowering the levels of GTP-bound, active Ras. The different isoforms may play a distinct role in specific tissues. | Rhomboid-related protein 1; Serine protease which activates lin-3 isoform a in the proximal vulva precursor cells (VPC) during vulva development to transmit the inductive anchor cell signal to the distal VPCs. | 0.476 |
| let-23 | gap-2 | ZK1067.1d.1 | ZK899.8c.1 | Receptor tyrosine-protein kinase let-23; Tyrosine-protein kinase receptor which, upon binding ligand lin-3, activates 2 signaling cascades: the let-60/Ras and MAP kinase signaling pathway and the let-60-independent phospholipase C-mediated Ca(2+) signaling pathway. Each pathway regulates distinct functions. By activating let-60/Ras, regulates larval development, induction of vulva cell precursors during vulva development, male spicule formation and posterior development of the epidermis. Probably by activating phospholipase plc-3 and inositol 1,4,5-trisphosphate receptor itr-1 signalin [...] | Ras GTPase-activating protein gap-2; GTPase-activating protein, which acts as a negative regulator for the member of the Ras family let-60. Probably decreases the signaling activity of Ras by stimulating its intrinsic GTPase activity, thereby lowering the levels of GTP-bound, active Ras. The different isoforms may play a distinct role in specific tissues. | 0.639 |
| let-23 | lin-3 | ZK1067.1d.1 | F36H1.4f.1 | Receptor tyrosine-protein kinase let-23; Tyrosine-protein kinase receptor which, upon binding ligand lin-3, activates 2 signaling cascades: the let-60/Ras and MAP kinase signaling pathway and the let-60-independent phospholipase C-mediated Ca(2+) signaling pathway. Each pathway regulates distinct functions. By activating let-60/Ras, regulates larval development, induction of vulva cell precursors during vulva development, male spicule formation and posterior development of the epidermis. Probably by activating phospholipase plc-3 and inositol 1,4,5-trisphosphate receptor itr-1 signalin [...] | Protein lin-3; Probable ligand for tyrosine kinase receptor let-23. Essential for vulval induction, where it acts downstream of the synthetic multivulva (synMuv) class genes. Probably by activating let-23, phospholipase plc-3 and inositol 1,4,5-trisphosphate receptor itr-1 signaling cascade, plays a role in ovulation by promoting gonadal sheath cell contractions and spermatheca dilatation during ovulation. Probably by regulating neuronal transmission in ALA neurons, mediates the decrease in pharyngeal pumping and locomotion during the quiescent state that precedes each larval molt, by [...] | 0.999 |
| let-23 | rom-1 | ZK1067.1d.1 | F26F4.3.1 | Receptor tyrosine-protein kinase let-23; Tyrosine-protein kinase receptor which, upon binding ligand lin-3, activates 2 signaling cascades: the let-60/Ras and MAP kinase signaling pathway and the let-60-independent phospholipase C-mediated Ca(2+) signaling pathway. Each pathway regulates distinct functions. By activating let-60/Ras, regulates larval development, induction of vulva cell precursors during vulva development, male spicule formation and posterior development of the epidermis. Probably by activating phospholipase plc-3 and inositol 1,4,5-trisphosphate receptor itr-1 signalin [...] | Rhomboid-related protein 1; Serine protease which activates lin-3 isoform a in the proximal vulva precursor cells (VPC) during vulva development to transmit the inductive anchor cell signal to the distal VPCs. | 0.526 |
| lin-3 | let-23 | F36H1.4f.1 | ZK1067.1d.1 | Protein lin-3; Probable ligand for tyrosine kinase receptor let-23. Essential for vulval induction, where it acts downstream of the synthetic multivulva (synMuv) class genes. Probably by activating let-23, phospholipase plc-3 and inositol 1,4,5-trisphosphate receptor itr-1 signaling cascade, plays a role in ovulation by promoting gonadal sheath cell contractions and spermatheca dilatation during ovulation. Probably by regulating neuronal transmission in ALA neurons, mediates the decrease in pharyngeal pumping and locomotion during the quiescent state that precedes each larval molt, by [...] | Receptor tyrosine-protein kinase let-23; Tyrosine-protein kinase receptor which, upon binding ligand lin-3, activates 2 signaling cascades: the let-60/Ras and MAP kinase signaling pathway and the let-60-independent phospholipase C-mediated Ca(2+) signaling pathway. Each pathway regulates distinct functions. By activating let-60/Ras, regulates larval development, induction of vulva cell precursors during vulva development, male spicule formation and posterior development of the epidermis. Probably by activating phospholipase plc-3 and inositol 1,4,5-trisphosphate receptor itr-1 signalin [...] | 0.999 |
| lin-3 | rom-1 | F36H1.4f.1 | F26F4.3.1 | Protein lin-3; Probable ligand for tyrosine kinase receptor let-23. Essential for vulval induction, where it acts downstream of the synthetic multivulva (synMuv) class genes. Probably by activating let-23, phospholipase plc-3 and inositol 1,4,5-trisphosphate receptor itr-1 signaling cascade, plays a role in ovulation by promoting gonadal sheath cell contractions and spermatheca dilatation during ovulation. Probably by regulating neuronal transmission in ALA neurons, mediates the decrease in pharyngeal pumping and locomotion during the quiescent state that precedes each larval molt, by [...] | Rhomboid-related protein 1; Serine protease which activates lin-3 isoform a in the proximal vulva precursor cells (VPC) during vulva development to transmit the inductive anchor cell signal to the distal VPCs. | 0.620 |
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