STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nhl-2NHL (Ring finger b-box coiled coil) domain containing. (1032 aa)    
Predicted Functional Partners:
cgh-1
ATP-dependent RNA helicase cgh-1; Probable RNA helicase required for oocyte and sperm function. Also required to prevent the physiological germline apoptosis mechanism killing essentially all developing oocytes. Belongs to the DEAD box helicase family. DDX6/DHH1 subfamily.
   
 
 0.929
ain-1
ALG-1 INteracting protein.
   
 
 0.916
alg-1
Protein argonaute; Belongs to the argonaute family.
   
 
 0.879
ain-2
ALG-1 INteracting protein.
   
 
 0.821
sup-26
SUPpressor.
   
  
 0.762
hbl-1
Hunchback-like protein; Required for the late stages of development. Plays a role in the developmental timing of postembryonic hypodermal seam cell fusion events and adult alae production.
   
 
 0.753
nhl-3
B box-type domain-containing protein.
      
 0.746
alg-2
Protein argonaute; Belongs to the argonaute family.
   
 
 0.714
wrt-3
Warthog protein 3; Intercellular signal essential for a variety of patterning events during development.
      
 0.695
C28G1.6
RING-type domain-containing protein.
    
 
 0.666
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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