node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
F08G12.1 | F26G1.9 | F08G12.1.1 | F26G1.9.1 | Uncharacterized protein. | DB domain-containing protein. | 0.448 |
F08G12.1 | nduo-4 | F08G12.1.1 | MTCE.25.1 | Uncharacterized protein. | NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. | 0.748 |
F14H12.3 | F26G1.9 | F14H12.3.1 | F26G1.9.1 | Uncharacterized protein. | DB domain-containing protein. | 0.525 |
F14H12.3 | ima-2 | F14H12.3.1 | F26B1.3.1 | Uncharacterized protein. | Importin subunit alpha-2; Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Promotes docking of import substrates to the nuclear envelope. Seems to act as a cytosolic receptor for both simple and bipartite NLS motifs (By similarity). | 0.562 |
F14H12.3 | ran-2 | F14H12.3.1 | C29E4.3a.1 | Uncharacterized protein. | Ran GTPase-activating protein 2; GTPase system comprising ran-1, ran-2 and ran-3 is essential in nucleocytoplasmic trafficking. Ran-2 is a GTPase activator for the nuclear RAS-related regulatory protein Ran, converting it to the putatively inactive GDP-bound state. Required for correct chromosome alignment and segregation on the metaphase plate. | 0.925 |
F26G1.9 | F08G12.1 | F26G1.9.1 | F08G12.1.1 | DB domain-containing protein. | Uncharacterized protein. | 0.448 |
F26G1.9 | F14H12.3 | F26G1.9.1 | F14H12.3.1 | DB domain-containing protein. | Uncharacterized protein. | 0.525 |
F26G1.9 | dph-3 | F26G1.9.1 | K01H12.1a.1 | DB domain-containing protein. | DPH3 homolog; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2 (By similarity). | 0.557 |
F26G1.9 | ima-2 | F26G1.9.1 | F26B1.3.1 | DB domain-containing protein. | Importin subunit alpha-2; Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Promotes docking of import substrates to the nuclear envelope. Seems to act as a cytosolic receptor for both simple and bipartite NLS motifs (By similarity). | 0.428 |
F26G1.9 | nduo-4 | F26G1.9.1 | MTCE.25.1 | DB domain-containing protein. | NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. | 0.631 |
F26G1.9 | rab-1 | F26G1.9.1 | C39F7.4.1 | DB domain-containing protein. | RAB family. | 0.448 |
F26G1.9 | rab-19 | F26G1.9.1 | Y62E10A.9.2 | DB domain-containing protein. | RAB family. | 0.448 |
F26G1.9 | rab-33 | F26G1.9.1 | F43D9.2.1 | DB domain-containing protein. | Ras-related protein Rab-33. | 0.448 |
F26G1.9 | ran-1 | F26G1.9.1 | K01G5.4.1 | DB domain-containing protein. | GTP-binding nuclear protein ran-1; Ran GTPase system comprises ran-1, ran-2 and ran-3 and is essential in nucleocytoplasmic transport. Ran-1 is a GTP-binding protein that mediates the interaction between mitotic chromosomes and kinetochore microtubules. Plays a crucial role in nuclear envelope assembly at the end of each cell division. Required for the import of protein into the nucleus and also for RNA export. RCC1 (ran-3)/Ran (ran-1) complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. | 0.525 |
F26G1.9 | ran-2 | F26G1.9.1 | C29E4.3a.1 | DB domain-containing protein. | Ran GTPase-activating protein 2; GTPase system comprising ran-1, ran-2 and ran-3 is essential in nucleocytoplasmic trafficking. Ran-2 is a GTPase activator for the nuclear RAS-related regulatory protein Ran, converting it to the putatively inactive GDP-bound state. Required for correct chromosome alignment and segregation on the metaphase plate. | 0.432 |
dph-3 | F26G1.9 | K01H12.1a.1 | F26G1.9.1 | DPH3 homolog; Required for the first step of diphthamide biosynthesis, the transfer of 3-amino-3-carboxypropyl from S-adenosyl-L-methionine to a histidine residue. Diphthamide is a post-translational modification of histidine which occurs in elongation factor 2 (By similarity). | DB domain-containing protein. | 0.557 |
ima-2 | F14H12.3 | F26B1.3.1 | F14H12.3.1 | Importin subunit alpha-2; Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Promotes docking of import substrates to the nuclear envelope. Seems to act as a cytosolic receptor for both simple and bipartite NLS motifs (By similarity). | Uncharacterized protein. | 0.562 |
ima-2 | F26G1.9 | F26B1.3.1 | F26G1.9.1 | Importin subunit alpha-2; Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Promotes docking of import substrates to the nuclear envelope. Seems to act as a cytosolic receptor for both simple and bipartite NLS motifs (By similarity). | DB domain-containing protein. | 0.428 |
ima-2 | ran-1 | F26B1.3.1 | K01G5.4.1 | Importin subunit alpha-2; Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Promotes docking of import substrates to the nuclear envelope. Seems to act as a cytosolic receptor for both simple and bipartite NLS motifs (By similarity). | GTP-binding nuclear protein ran-1; Ran GTPase system comprises ran-1, ran-2 and ran-3 and is essential in nucleocytoplasmic transport. Ran-1 is a GTP-binding protein that mediates the interaction between mitotic chromosomes and kinetochore microtubules. Plays a crucial role in nuclear envelope assembly at the end of each cell division. Required for the import of protein into the nucleus and also for RNA export. RCC1 (ran-3)/Ran (ran-1) complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. | 0.869 |
ima-2 | ran-2 | F26B1.3.1 | C29E4.3a.1 | Importin subunit alpha-2; Binds specifically and directly to substrates containing either a simple or bipartite NLS motif. Promotes docking of import substrates to the nuclear envelope. Seems to act as a cytosolic receptor for both simple and bipartite NLS motifs (By similarity). | Ran GTPase-activating protein 2; GTPase system comprising ran-1, ran-2 and ran-3 is essential in nucleocytoplasmic trafficking. Ran-2 is a GTPase activator for the nuclear RAS-related regulatory protein Ran, converting it to the putatively inactive GDP-bound state. Required for correct chromosome alignment and segregation on the metaphase plate. | 0.760 |