STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
exl-1Chloride intracellular channel exl-1; Probable chloride channel; Belongs to the chloride channel CLIC family. (238 aa)    
Predicted Functional Partners:
F23H12.5
Uncharacterized protein.
      
 0.694
Y73E7A.8
Uncharacterized protein.
      
 0.694
cdh-5
CaDHerin family.
    
 
 0.672
F16F9.4
Uncharacterized protein.
      
 0.670
ham-1
Stork_head domain-containing protein.
      
 0.656
exc-4
Chloride intracellular channel exc-4; May insert into membranes and form chloride ion channels. Involved in the formation of the excretory canal. Required to prevent cystic lumenal expansions in the excretory cell. Not required for formation of the initial tube, but is required for regulating the size of the tube lumen as it grows.
    
 
0.601
yap-1
Yes-associated protein homolog 1; Plays a role in thermal stress response and in aging.
    
 
 0.594
col-101
Col_cuticle_N domain-containing protein.
      
 0.486
fer-1
Sperm vesicle fusion protein fer-1; Required for the fusion of the membranous organelles (MOs) with the plasma membrane, a process essential in spermiogenesis.
      
 0.477
ferl-1
FER-1 Like.
      
 0.477
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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