node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C08B11.8 | aagr-4 | C08B11.8.1 | F52D1.1.1 | Probable dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase; Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation (By similarity). Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol (By similarity). Belongs to the ALG6/ALG8 glucosyltransferase family. | Gal_mutarotas_2 domain-containing protein; Belongs to the glycosyl hydrolase 31 family. | 0.499 |
C08B11.8 | cnx-1 | C08B11.8.1 | ZK632.6a.1 | Probable dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase; Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation (By similarity). Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol (By similarity). Belongs to the ALG6/ALG8 glucosyltransferase family. | Calnexin; Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins (By similarity). Required for embryogenesis and larval development under heat and ER stress conditions. May be important for germ cell development. Involved in neuronal necrotic cell death. | 0.652 |
C08B11.8 | ribo-1 | C08B11.8.1 | T22D1.4.1 | Probable dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase; Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation (By similarity). Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol (By similarity). Belongs to the ALG6/ALG8 glucosyltransferase family. | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] | 0.512 |
C08B11.8 | stt-3 | C08B11.8.1 | T12A2.2.1 | Probable dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase; Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation (By similarity). Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol (By similarity). Belongs to the ALG6/ALG8 glucosyltransferase family. | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit stt-3; Catalytic subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation [...] | 0.719 |
C08B11.8 | uggt-2 | C08B11.8.1 | F26H9.8.1 | Probable dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase; Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation (By similarity). Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol (By similarity). Belongs to the ALG6/ALG8 glucosyltransferase family. | UDP-Glucose Glycoprotein glucosylTransferase. | 0.535 |
F01G10.10 | uggt-2 | F01G10.10.1 | F26H9.8.1 | Uncharacterized protein. | UDP-Glucose Glycoprotein glucosylTransferase. | 0.741 |
Y73B6BL.12 | aagr-4 | Y73B6BL.12.1 | F52D1.1.1 | Thioredoxin; Belongs to the thioredoxin family. | Gal_mutarotas_2 domain-containing protein; Belongs to the glycosyl hydrolase 31 family. | 0.540 |
Y73B6BL.12 | cnx-1 | Y73B6BL.12.1 | ZK632.6a.1 | Thioredoxin; Belongs to the thioredoxin family. | Calnexin; Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins (By similarity). Required for embryogenesis and larval development under heat and ER stress conditions. May be important for germ cell development. Involved in neuronal necrotic cell death. | 0.746 |
Y73B6BL.12 | crt-1 | Y73B6BL.12.1 | Y38A10A.5.2 | Thioredoxin; Belongs to the thioredoxin family. | Calreticulin; Molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle (By similarity). This lectin may interact transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER (By similarity). Probably by controlling the folding of extracellular matrix protein unc-52/Perlecan, may play a role in the formation of fibrous organelles, a hemidesmosome-like structure attaching muscles to the epidermis. Protects dopaminergic neurons against oxidative stress-induced neurodegen [...] | 0.832 |
Y73B6BL.12 | hsp-3 | Y73B6BL.12.1 | C15H9.6a.5 | Thioredoxin; Belongs to the thioredoxin family. | Heat shock 70 kDa protein C; Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. | 0.941 |
Y73B6BL.12 | ribo-1 | Y73B6BL.12.1 | T22D1.4.1 | Thioredoxin; Belongs to the thioredoxin family. | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] | 0.405 |
Y73B6BL.12 | stt-3 | Y73B6BL.12.1 | T12A2.2.1 | Thioredoxin; Belongs to the thioredoxin family. | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit stt-3; Catalytic subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation [...] | 0.452 |
Y73B6BL.12 | uggt-2 | Y73B6BL.12.1 | F26H9.8.1 | Thioredoxin; Belongs to the thioredoxin family. | UDP-Glucose Glycoprotein glucosylTransferase. | 0.537 |
aagr-4 | C08B11.8 | F52D1.1.1 | C08B11.8.1 | Gal_mutarotas_2 domain-containing protein; Belongs to the glycosyl hydrolase 31 family. | Probable dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase; Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation (By similarity). Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol (By similarity). Belongs to the ALG6/ALG8 glucosyltransferase family. | 0.499 |
aagr-4 | Y73B6BL.12 | F52D1.1.1 | Y73B6BL.12.1 | Gal_mutarotas_2 domain-containing protein; Belongs to the glycosyl hydrolase 31 family. | Thioredoxin; Belongs to the thioredoxin family. | 0.540 |
aagr-4 | cnx-1 | F52D1.1.1 | ZK632.6a.1 | Gal_mutarotas_2 domain-containing protein; Belongs to the glycosyl hydrolase 31 family. | Calnexin; Calcium-binding protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may act in assisting protein assembly and/or in the retention within the ER of unassembled protein subunits. It seems to play a major role in the quality control apparatus of the ER by the retention of incorrectly folded proteins (By similarity). Required for embryogenesis and larval development under heat and ER stress conditions. May be important for germ cell development. Involved in neuronal necrotic cell death. | 0.833 |
aagr-4 | crt-1 | F52D1.1.1 | Y38A10A.5.2 | Gal_mutarotas_2 domain-containing protein; Belongs to the glycosyl hydrolase 31 family. | Calreticulin; Molecular calcium-binding chaperone promoting folding, oligomeric assembly and quality control in the ER via the calreticulin/calnexin cycle (By similarity). This lectin may interact transiently with almost all of the monoglucosylated glycoproteins that are synthesized in the ER (By similarity). Probably by controlling the folding of extracellular matrix protein unc-52/Perlecan, may play a role in the formation of fibrous organelles, a hemidesmosome-like structure attaching muscles to the epidermis. Protects dopaminergic neurons against oxidative stress-induced neurodegen [...] | 0.513 |
aagr-4 | hsp-3 | F52D1.1.1 | C15H9.6a.5 | Gal_mutarotas_2 domain-containing protein; Belongs to the glycosyl hydrolase 31 family. | Heat shock 70 kDa protein C; Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. | 0.494 |
aagr-4 | ribo-1 | F52D1.1.1 | T22D1.4.1 | Gal_mutarotas_2 domain-containing protein; Belongs to the glycosyl hydrolase 31 family. | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] | 0.776 |
aagr-4 | stt-3 | F52D1.1.1 | T12A2.2.1 | Gal_mutarotas_2 domain-containing protein; Belongs to the glycosyl hydrolase 31 family. | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit stt-3; Catalytic subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation [...] | 0.401 |