node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C32E8.9 | F02A9.10 | C32E8.9.1 | F02A9.10.1 | Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. | Probable methylcrotonoyl-CoA carboxylase beta chain, mitochondrial; Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3- methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism; Belongs to the AccD/PCCB family. | 0.616 |
C32E8.9 | acox-1.1 | C32E8.9.1 | F08A8.1a.1 | Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | 0.967 |
C32E8.9 | acox-1.2 | C32E8.9.1 | F08A8.2.1 | Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | 0.967 |
C32E8.9 | acox-1.3 | C32E8.9.1 | F08A8.3.1 | Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | 0.967 |
C32E8.9 | acox-1.5 | C32E8.9.1 | C48B4.1.1 | Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. | Probable peroxisomal acyl-coenzyme A oxidase 1.5; Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl- CoAs. | 0.967 |
C32E8.9 | alh-8 | C32E8.9.1 | F13D12.4a.3 | Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. | Probable methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA (By similarity); Belongs to the aldehyde dehydrogenase family. | 0.938 |
C32E8.9 | dbt-1 | C32E8.9.1 | ZK669.4.1 | Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. | 2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase); The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2) (By similarity). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). Within this complex, the catalytic function of this enzyme is to accept, and to transfer to coenzyme A, acyl groups that are generated by the branched-chain alpha-keto acid decarboxyl [...] | 0.927 |
C32E8.9 | mce-1 | C32E8.9.1 | D2030.5.1 | Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. | Mitochondrial methylmalonyl-CoA epimerase. | 0.955 |
C32E8.9 | pcca-1 | C32E8.9.1 | F27D9.5.2 | Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. | Propionyl-CoA carboxylase alpha chain, mitochondrial; This is one of the 2 subunits of the biotin-dependent propionyl-CoA carboxylase (PCC), a mitochondrial enzyme involved in the catabolism of odd chain fatty acids, branched-chain amino acids isoleucine, threonine, methionine, and valine and other metabolites. Propionyl-CoA carboxylase catalyzes the carboxylation of propionyl- CoA/propanoyl-CoA to D-methylmalonyl-CoA/(S)-methylmalonyl-CoA (By similarity). Within the holoenzyme, the alpha subunit catalyzes the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl car [...] | 0.957 |
C32E8.9 | pccb-1 | C32E8.9.1 | F52E4.1a.2 | Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. | Propionyl Coenzyme A Carboxylase Beta subunit. | 0.960 |
F02A9.10 | C32E8.9 | F02A9.10.1 | C32E8.9.1 | Probable methylcrotonoyl-CoA carboxylase beta chain, mitochondrial; Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3- methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism; Belongs to the AccD/PCCB family. | Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. | 0.616 |
F02A9.10 | acox-1.1 | F02A9.10.1 | F08A8.1a.1 | Probable methylcrotonoyl-CoA carboxylase beta chain, mitochondrial; Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3- methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism; Belongs to the AccD/PCCB family. | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | 0.601 |
F02A9.10 | acox-1.2 | F02A9.10.1 | F08A8.2.1 | Probable methylcrotonoyl-CoA carboxylase beta chain, mitochondrial; Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3- methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism; Belongs to the AccD/PCCB family. | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | 0.601 |
F02A9.10 | acox-1.3 | F02A9.10.1 | F08A8.3.1 | Probable methylcrotonoyl-CoA carboxylase beta chain, mitochondrial; Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3- methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism; Belongs to the AccD/PCCB family. | Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. | 0.601 |
F02A9.10 | acox-1.5 | F02A9.10.1 | C48B4.1.1 | Probable methylcrotonoyl-CoA carboxylase beta chain, mitochondrial; Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3- methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism; Belongs to the AccD/PCCB family. | Probable peroxisomal acyl-coenzyme A oxidase 1.5; Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl- CoAs. | 0.601 |
F02A9.10 | alh-8 | F02A9.10.1 | F13D12.4a.3 | Probable methylcrotonoyl-CoA carboxylase beta chain, mitochondrial; Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3- methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism; Belongs to the AccD/PCCB family. | Probable methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; Plays a role in valine and pyrimidine metabolism. Binds fatty acyl-CoA (By similarity); Belongs to the aldehyde dehydrogenase family. | 0.522 |
F02A9.10 | dbt-1 | F02A9.10.1 | ZK669.4.1 | Probable methylcrotonoyl-CoA carboxylase beta chain, mitochondrial; Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3- methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism; Belongs to the AccD/PCCB family. | 2-oxoisovalerate dehydrogenase E2 component (dihydrolipoyl transacylase); The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2) (By similarity). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). Within this complex, the catalytic function of this enzyme is to accept, and to transfer to coenzyme A, acyl groups that are generated by the branched-chain alpha-keto acid decarboxyl [...] | 0.816 |
F02A9.10 | mce-1 | F02A9.10.1 | D2030.5.1 | Probable methylcrotonoyl-CoA carboxylase beta chain, mitochondrial; Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3- methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism; Belongs to the AccD/PCCB family. | Mitochondrial methylmalonyl-CoA epimerase. | 0.824 |
F02A9.10 | pcca-1 | F02A9.10.1 | F27D9.5.2 | Probable methylcrotonoyl-CoA carboxylase beta chain, mitochondrial; Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3- methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism; Belongs to the AccD/PCCB family. | Propionyl-CoA carboxylase alpha chain, mitochondrial; This is one of the 2 subunits of the biotin-dependent propionyl-CoA carboxylase (PCC), a mitochondrial enzyme involved in the catabolism of odd chain fatty acids, branched-chain amino acids isoleucine, threonine, methionine, and valine and other metabolites. Propionyl-CoA carboxylase catalyzes the carboxylation of propionyl- CoA/propanoyl-CoA to D-methylmalonyl-CoA/(S)-methylmalonyl-CoA (By similarity). Within the holoenzyme, the alpha subunit catalyzes the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl car [...] | 0.998 |
F02A9.10 | pccb-1 | F02A9.10.1 | F52E4.1a.2 | Probable methylcrotonoyl-CoA carboxylase beta chain, mitochondrial; Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3- methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism; Belongs to the AccD/PCCB family. | Propionyl Coenzyme A Carboxylase Beta subunit. | 0.587 |