STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F28C1.1DRY_EERY domain-containing protein. (672 aa)    
Predicted Functional Partners:
uri-1
URI (Unconventional prefoldin RPB5 Interactor) homolog.
   
  
 0.596
prpf-4
Protein kinase domain-containing protein.
   
  
 0.562
pafo-1
RNA polymerase II-associated factor 1 homolog; Component of the PAF1 complex which is a multifunctional complex involved in transcription initiation via genetic interactions with TATA-binding proteins, elongation and transcription-coupled histone modification.
   
  
 0.532
gkow-1
G-patch domain and KOW motifs-containing protein homolog 1; Belongs to the MOS2 family.
   
    0.525
K07C5.6
Pre-mRNA-splicing factor SLU7; Participates in the second catalytic step of pre-mRNA splicing, when the free hydroxyl group of exon I attacks the 3'-splice site to generate spliced mRNA and the excised lariat intron. Belongs to the SLU7 family.
   
    0.522
ari-1.2
RBR-type E3 ubiquitin transferase.
   
  
 0.495
lact-3
Beta-lactamase domain-containing protein.
   
  
 0.488
ZK973.11
Thioredoxin domain-containing protein.
   
  
 0.481
T20F5.6
RING-type domain-containing protein.
   
  
 0.478
ari-2
Potential E3 ubiquitin-protein ligase ariadne-2; Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBC-2/UBE2L3, and then transfers it to substrates. Belongs to the RBR family. Ariadne subfamily.
   
  
 0.473
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.