STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aptf-3TF_AP-2 domain-containing protein. (535 aa)    
Predicted Functional Partners:
aptf-2
TF_AP-2 domain-containing protein.
   
0.858
aptf-1
Transcription factor aptf-1; Transcription factor, which is required in the single sleep- active ring interneuron RIS for sleep-like behavioral quiescence induced by neuropeptide signaling in larvae. Regulates gene expression of sleep-inducing FMRFamide-like neuropeptide flp-11 in RIS.
     
0.615
Y105E8B.7
Uncharacterized protein.
    
 0.546
nos-1
Nanos-type domain-containing protein; Belongs to the nanos family.
   
  
 0.444
aptf-4
TF_AP-2 domain-containing protein.
   
 
0.439
B0393.6
RING-type domain-containing protein.
   
    0.433
memi-3
MEiosis-to-MItosis transition associated.
   
    0.420
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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