STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acs-2Fatty Acid CoA Synthetase family. (618 aa)    
Predicted Functional Partners:
fasn-1
Carrier domain-containing protein.
 
 0.969
ech-1.1
Enoyl-CoA Hydratase.
  
 0.953
pks-1
PolyKetide Synthase.
  
 0.941
cpt-1
Carnitine Palmitoyl Transferase; Belongs to the carnitine/choline acetyltransferase family.
     
 0.940
W03F9.4
Carn_acyltransf domain-containing protein.
     
  0.900
npp-11
Nuclear Pore complex Protein.
   
 
 0.877
hacd-1
Hydroxy-Acyl-CoA Dehydrogenase.
  
 
 0.873
icl-1
Bifunctional glyoxylate cycle protein; In the C-terminal section; belongs to the malate synthase family.
  
 
 0.857
nhr-49
Nuclear hormone receptor family member nhr-49; Orphan nuclear receptor. Regulates expression of lipid desaturase, fat-7 ; Belongs to the nuclear hormone receptor family.
    
 
 0.855
fat-7
Delta(9)-fatty-acid desaturase fat-7; Delta(9)-fatty-acid desaturase that acts preferentially on stearoyl-CoA. Also acts on vaccenyl-coA, heptadecanyol-CoA, and palmitoyl-CoA.
      
 0.851
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.