STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sqv-4UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (481 aa)    
Predicted Functional Partners:
sqv-1
NAD(P)-bd_dom domain-containing protein.
 0.999
C01F1.3
NAD(P)-bd_dom domain-containing protein.
  
 
 0.991
C14F11.6
Uncharacterized protein.
  
  
 0.989
gale-1
UDP-glucose 4-epimerase; Catalyzes two distinct but analogous reactions: the reversible epimerization of UDP-glucose to UDP-galactose and the reversible epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine. The reaction with UDP-Gal plays a critical role in the Leloir pathway of galactose catabolism in which galactose is converted to the glycolytic intermediate glucose 6-phosphate. It contributes to the catabolism of dietary galactose and enables the endogenous biosynthesis of both UDP-Gal and UDP-GalNAc when exogenous sources are limited. Both UDP-sugar interconversi [...]
  
 
 0.989
K08E3.5
UTP--glucose-1-phosphate uridylyltransferase.
     
 0.961
F53B1.4
NAD(P)-bd_dom domain-containing protein.
  
  
 0.923
ugt-62
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
   
 
 0.905
ugt-46
Putative UDP-glucuronosyltransferase ugt-46; Belongs to the UDP-glycosyltransferase family.
     
 0.903
ugt-23
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
     
 0.903
ugt-48
Putative UDP-glucuronosyltransferase ugt-48.
     
 0.903
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.