STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gras-1PDZ domain-containing protein. (245 aa)    
Predicted Functional Partners:
T01C3.3
RING-type domain-containing protein.
   
  
 0.865
C06A5.8
RING-type domain-containing protein.
   
 
 0.858
gipc-2
PDZ domain-containing protein.
      
 0.817
Y54E5A.7
Uncharacterized protein.
   
 
 0.813
smz-2
Sperm Meiosis PDZ domain containing proteins.
      
 0.811
smz-1
Sperm Meiosis PDZ domain containing proteins.
      
 0.810
gipc-1
PDZ domain-containing protein.
      
 0.756
aipr-1
Aryl hydrocarbon receptor Interacting Protein (AIP) Related.
   
  
 0.731
ubc-6
UBIQUITIN_CONJUGAT_2 domain-containing protein.
   
 
 0.705
pxf-1
Rap guanine nucleotide exchange factor; Acts as a guanine nucleotide exchange factor for small G protein GTPases like rap-1 and rap-2. Required in the hypodermis, especially in the seam cells, for proper formation of the cuticle. Belongs to the RAPGEF2 family.
   
  
 0.700
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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