STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
arg-1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (357 aa)    
Predicted Functional Partners:
hlh-8
Twist-related protein; Acts as a transcriptional regulator. Involved in postembryonic mesodermal cell fate specification. Activates ceh-24 and egl-15 during mesodermal patterning.
   
 
 0.831
ehn-3
Zinc finger protein ehn-3; Together with the zinc finger protein ztf-16, plays a role in gonadogenesis, specifically in somatic gonad precursor cell development. This is possibly by regulating tra-1 gene expression. Belongs to the krueppel C2H2-type zinc-finger protein family.
    
 
 0.830
C46E10.8
Uncharacterized protein.
    
 
 0.779
dsl-5
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
      
 0.741
ztf-16
Zinc finger protein ztf-16; Positively regulates the expression of ver-1 in the amphid sheath glia of amphid sensory neurons. Together with ehn-3, plays a role in somatic gonad development and is required for proper gonadal primordium assembly and somatic gonad precursor cell morphology ; Belongs to the Ikaros C2H2-type zinc-finger protein family.
    
 
 0.725
slc-25A18.1
SLC (SoLute Carrier) homolog; Belongs to the mitochondrial carrier (TC 2.A.29) family.
    
 
 0.704
bgal-1
Beta-galactosidase.
   
  
 0.700
dsl-7
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
      
 0.699
K09C8.2
Uncharacterized protein.
      
 0.698
dsl-6
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
      
 0.697
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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