node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C49A9.3 | F21C10.7 | C49A9.3.1 | F21C10.7.1 | Uncharacterized protein. | Uncharacterized protein. | 0.815 |
C49A9.3 | cpna-1 | C49A9.3.1 | F31D5.3b.1 | Uncharacterized protein. | Copine family protein 1; Involved in the assembly of dense bodies and M lines during body wall muscle development. Acts by recruiting downstream of integrin-associated protein pat-6/actopaxin several dense bodies and M line components including unc-89, lim-9, scpl-1 and unc-96 to integrin- mediated attachment sites. | 0.698 |
C49A9.9 | F21C10.7 | C49A9.9a.3 | F21C10.7.1 | Uncharacterized protein. | Uncharacterized protein. | 0.814 |
C49A9.9 | cpna-1 | C49A9.9a.3 | F31D5.3b.1 | Uncharacterized protein. | Copine family protein 1; Involved in the assembly of dense bodies and M lines during body wall muscle development. Acts by recruiting downstream of integrin-associated protein pat-6/actopaxin several dense bodies and M line components including unc-89, lim-9, scpl-1 and unc-96 to integrin- mediated attachment sites. | 0.695 |
F21C10.7 | C49A9.3 | F21C10.7.1 | C49A9.3.1 | Uncharacterized protein. | Uncharacterized protein. | 0.815 |
F21C10.7 | C49A9.9 | F21C10.7.1 | C49A9.9a.3 | Uncharacterized protein. | Uncharacterized protein. | 0.814 |
F21C10.7 | cpna-1 | F21C10.7.1 | F31D5.3b.1 | Uncharacterized protein. | Copine family protein 1; Involved in the assembly of dense bodies and M lines during body wall muscle development. Acts by recruiting downstream of integrin-associated protein pat-6/actopaxin several dense bodies and M line components including unc-89, lim-9, scpl-1 and unc-96 to integrin- mediated attachment sites. | 0.721 |
cpna-1 | C49A9.3 | F31D5.3b.1 | C49A9.3.1 | Copine family protein 1; Involved in the assembly of dense bodies and M lines during body wall muscle development. Acts by recruiting downstream of integrin-associated protein pat-6/actopaxin several dense bodies and M line components including unc-89, lim-9, scpl-1 and unc-96 to integrin- mediated attachment sites. | Uncharacterized protein. | 0.698 |
cpna-1 | C49A9.9 | F31D5.3b.1 | C49A9.9a.3 | Copine family protein 1; Involved in the assembly of dense bodies and M lines during body wall muscle development. Acts by recruiting downstream of integrin-associated protein pat-6/actopaxin several dense bodies and M line components including unc-89, lim-9, scpl-1 and unc-96 to integrin- mediated attachment sites. | Uncharacterized protein. | 0.695 |
cpna-1 | F21C10.7 | F31D5.3b.1 | F21C10.7.1 | Copine family protein 1; Involved in the assembly of dense bodies and M lines during body wall muscle development. Acts by recruiting downstream of integrin-associated protein pat-6/actopaxin several dense bodies and M line components including unc-89, lim-9, scpl-1 and unc-96 to integrin- mediated attachment sites. | Uncharacterized protein. | 0.721 |
cpna-1 | cpna-4 | F31D5.3b.1 | Y73F8A.19.1 | Copine family protein 1; Involved in the assembly of dense bodies and M lines during body wall muscle development. Acts by recruiting downstream of integrin-associated protein pat-6/actopaxin several dense bodies and M line components including unc-89, lim-9, scpl-1 and unc-96 to integrin- mediated attachment sites. | Copine domain-containing protein. | 0.851 |
cpna-1 | lim-9 | F31D5.3b.1 | F25H5.1i.1 | Copine family protein 1; Involved in the assembly of dense bodies and M lines during body wall muscle development. Acts by recruiting downstream of integrin-associated protein pat-6/actopaxin several dense bodies and M line components including unc-89, lim-9, scpl-1 and unc-96 to integrin- mediated attachment sites. | LIM domain family. | 0.892 |
cpna-1 | mel-26 | F31D5.3b.1 | ZK858.4b.1 | Copine family protein 1; Involved in the assembly of dense bodies and M lines during body wall muscle development. Acts by recruiting downstream of integrin-associated protein pat-6/actopaxin several dense bodies and M line components including unc-89, lim-9, scpl-1 and unc-96 to integrin- mediated attachment sites. | Protein maternal effect lethal 26; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Controls degradation of microtubule severing protein mei-1 after meiosis. Controls degradation of ppfr-1, the regulatory subunit of PP4 complex, after meiosis. In body wall muscles, involved in the organization of myosin thick filaments, likely by regulating the degradation of mei-1 downstream of unc-89. May also activate the TORC1 pathway. | 0.849 |
cpna-1 | pat-6 | F31D5.3b.1 | T21D12.4.1 | Copine family protein 1; Involved in the assembly of dense bodies and M lines during body wall muscle development. Acts by recruiting downstream of integrin-associated protein pat-6/actopaxin several dense bodies and M line components including unc-89, lim-9, scpl-1 and unc-96 to integrin- mediated attachment sites. | Paralyzed arrest at two-fold protein 6; Involved in the regulation of cell adhesion and cytoskeleton organization. Component of an integrin containing attachment complex, which is required for muscle development and maintenance. During embryonic development, required to recruit cpna-1, unc-89 and myofilaments to newly forming integrin attachments composed of integrins pat-2/pat-3, pat-4 and unc-112. Also required to reposition the integrin-based attachments so that they form the highly ordered array of dense body and M-line attachments that are characteristic of mature muscle cells. Du [...] | 0.847 |
cpna-1 | scpl-1 | F31D5.3b.1 | B0379.4b.1 | Copine family protein 1; Involved in the assembly of dense bodies and M lines during body wall muscle development. Acts by recruiting downstream of integrin-associated protein pat-6/actopaxin several dense bodies and M line components including unc-89, lim-9, scpl-1 and unc-96 to integrin- mediated attachment sites. | CTD small phosphatase-like protein 1; Phosphatase which may play a role in the egg laying muscles. | 0.883 |
cpna-1 | unc-96 | F31D5.3b.1 | F13C5.6b.1 | Copine family protein 1; Involved in the assembly of dense bodies and M lines during body wall muscle development. Acts by recruiting downstream of integrin-associated protein pat-6/actopaxin several dense bodies and M line components including unc-89, lim-9, scpl-1 and unc-96 to integrin- mediated attachment sites. | Uncharacterized protein. | 0.837 |
cpna-1 | unc-97 | F31D5.3b.1 | F14D12.2.1 | Copine family protein 1; Involved in the assembly of dense bodies and M lines during body wall muscle development. Acts by recruiting downstream of integrin-associated protein pat-6/actopaxin several dense bodies and M line components including unc-89, lim-9, scpl-1 and unc-96 to integrin- mediated attachment sites. | LIM domain-containing protein unc-97; Component of an integrin containing attachment complex, which is required for muscle development and maintenance. Probably function in adherens junction. Affects the structural integrity of the integrin containing muscle adherens junctions and contributes to the mechanosensory functions of touch neurons. | 0.703 |
cpna-4 | cpna-1 | Y73F8A.19.1 | F31D5.3b.1 | Copine domain-containing protein. | Copine family protein 1; Involved in the assembly of dense bodies and M lines during body wall muscle development. Acts by recruiting downstream of integrin-associated protein pat-6/actopaxin several dense bodies and M line components including unc-89, lim-9, scpl-1 and unc-96 to integrin- mediated attachment sites. | 0.851 |
cpna-4 | lim-9 | Y73F8A.19.1 | F25H5.1i.1 | Copine domain-containing protein. | LIM domain family. | 0.692 |
cpna-4 | mel-26 | Y73F8A.19.1 | ZK858.4b.1 | Copine domain-containing protein. | Protein maternal effect lethal 26; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Controls degradation of microtubule severing protein mei-1 after meiosis. Controls degradation of ppfr-1, the regulatory subunit of PP4 complex, after meiosis. In body wall muscles, involved in the organization of myosin thick filaments, likely by regulating the degradation of mei-1 downstream of unc-89. May also activate the TORC1 pathway. | 0.617 |