node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ags-3 | alh-13 | F32A6.4a.1 | T22H6.2b.1 | Activator of G protein Signalling. | Probable delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.813 |
ags-3 | dlg-1 | F32A6.4a.1 | C25F6.2a.1 | Activator of G protein Signalling. | Disks large homolog 1; Essential multidomain scaffolding protein required for normal development (Probable). Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells (By similarity). Required for proper embryonic elongation. Acts upstream of ajm-1 and becomes localized to apical junctions independently of ajm-1. With let-413, cooperatively regulates ajm-1 localization to apical junctions. Belongs to the MAGUK family. | 0.905 |
ags-3 | gbas-1 | F32A6.4a.1 | F59H5.1.1 | Activator of G protein Signalling. | G-protein alpha subunit activating protein gbas-1; Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates G-protein alpha subunit goa-1. | 0.809 |
ags-3 | goa-1 | F32A6.4a.1 | C26C6.2.1 | Activator of G protein Signalling. | Guanine nucleotide-binding protein G(o) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(o) protein function is not clear. In the 1-cell embryo, probably together with gpa-16, controls nuclear rotation and spindle elongation during mitosis. During the first embryonic cell divisions, plays a role in gpr-1/2 cortical localization and in the proper orientation of EMS blastomere mitotic spindle. Polarity determinants (par genes) may regulate lin- 5/gpr-1/gpr-2/goa-1 locally to create [...] | 0.905 |
ags-3 | gpa-16 | F32A6.4a.1 | Y95B8A.5a.1 | Activator of G protein Signalling. | Guanine nucleotide-binding protein alpha-16 subunit; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. In the 1-cell embryo, probably together with goa-1, controls nuclear rotation and spindle elongation during mitosis. During the first embryonic cell divisons, plays a role in gpr-1/2 cortical localization and in the proper orientation of EMS blastomere mitotic spindle. Belongs to the G-alpha family. | 0.886 |
ags-3 | gpr-1 | F32A6.4a.1 | F22B7.13.1 | Activator of G protein Signalling. | G-protein regulator 1; In the 1-cell embryo, probably together with gpr-2, controls nuclear rotation and spindle elongation during mitosis. Complex of gpr-1 and gpr-2, in association with lin- 5, activates G-protein signaling to affect mitotic spindle force. Polarity determinants (par genes) may regulate lin- 5/gpr-1/gpr-2/goa-1 locally to create the asymmetric forces that drive spindle movement. | 0.809 |
ags-3 | insc-1 | F32A6.4a.1 | F43E2.3b.1 | Activator of G protein Signalling. | INSCuteable (Drososphila asymmetric cell division protein) homolog. | 0.900 |
ags-3 | magu-2 | F32A6.4a.1 | C01B7.4a.2 | Activator of G protein Signalling. | MAGUK family; Belongs to the MAGUK family. | 0.867 |
ags-3 | magu-4 | F32A6.4a.1 | F44D12.1a.1 | Activator of G protein Signalling. | MAGUK family. | 0.855 |
ags-3 | ppk-1 | F32A6.4a.1 | F55A12.3.1 | Activator of G protein Signalling. | PIPK domain-containing protein. | 0.924 |
alh-13 | ags-3 | T22H6.2b.1 | F32A6.4a.1 | Probable delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Activator of G protein Signalling. | 0.813 |
alh-13 | gbas-1 | T22H6.2b.1 | F59H5.1.1 | Probable delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | G-protein alpha subunit activating protein gbas-1; Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates G-protein alpha subunit goa-1. | 0.691 |
alh-13 | goa-1 | T22H6.2b.1 | C26C6.2.1 | Probable delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Guanine nucleotide-binding protein G(o) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(o) protein function is not clear. In the 1-cell embryo, probably together with gpa-16, controls nuclear rotation and spindle elongation during mitosis. During the first embryonic cell divisions, plays a role in gpr-1/2 cortical localization and in the proper orientation of EMS blastomere mitotic spindle. Polarity determinants (par genes) may regulate lin- 5/gpr-1/gpr-2/goa-1 locally to create [...] | 0.706 |
alh-13 | gpa-16 | T22H6.2b.1 | Y95B8A.5a.1 | Probable delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | Guanine nucleotide-binding protein alpha-16 subunit; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. In the 1-cell embryo, probably together with goa-1, controls nuclear rotation and spindle elongation during mitosis. During the first embryonic cell divisons, plays a role in gpr-1/2 cortical localization and in the proper orientation of EMS blastomere mitotic spindle. Belongs to the G-alpha family. | 0.817 |
alh-13 | gpr-1 | T22H6.2b.1 | F22B7.13.1 | Probable delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | G-protein regulator 1; In the 1-cell embryo, probably together with gpr-2, controls nuclear rotation and spindle elongation during mitosis. Complex of gpr-1 and gpr-2, in association with lin- 5, activates G-protein signaling to affect mitotic spindle force. Polarity determinants (par genes) may regulate lin- 5/gpr-1/gpr-2/goa-1 locally to create the asymmetric forces that drive spindle movement. | 0.806 |
dlg-1 | ags-3 | C25F6.2a.1 | F32A6.4a.1 | Disks large homolog 1; Essential multidomain scaffolding protein required for normal development (Probable). Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells (By similarity). Required for proper embryonic elongation. Acts upstream of ajm-1 and becomes localized to apical junctions independently of ajm-1. With let-413, cooperatively regulates ajm-1 localization to apical junctions. Belongs to the MAGUK family. | Activator of G protein Signalling. | 0.905 |
dlg-1 | magu-2 | C25F6.2a.1 | C01B7.4a.2 | Disks large homolog 1; Essential multidomain scaffolding protein required for normal development (Probable). Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells (By similarity). Required for proper embryonic elongation. Acts upstream of ajm-1 and becomes localized to apical junctions independently of ajm-1. With let-413, cooperatively regulates ajm-1 localization to apical junctions. Belongs to the MAGUK family. | MAGUK family; Belongs to the MAGUK family. | 0.590 |
gbas-1 | ags-3 | F59H5.1.1 | F32A6.4a.1 | G-protein alpha subunit activating protein gbas-1; Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates G-protein alpha subunit goa-1. | Activator of G protein Signalling. | 0.809 |
gbas-1 | alh-13 | F59H5.1.1 | T22H6.2b.1 | G-protein alpha subunit activating protein gbas-1; Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates G-protein alpha subunit goa-1. | Probable delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family. | 0.691 |
gbas-1 | goa-1 | F59H5.1.1 | C26C6.2.1 | G-protein alpha subunit activating protein gbas-1; Acts as a non-receptor guanine nucleotide exchange factor which binds to and activates G-protein alpha subunit goa-1. | Guanine nucleotide-binding protein G(o) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(o) protein function is not clear. In the 1-cell embryo, probably together with gpa-16, controls nuclear rotation and spindle elongation during mitosis. During the first embryonic cell divisions, plays a role in gpr-1/2 cortical localization and in the proper orientation of EMS blastomere mitotic spindle. Polarity determinants (par genes) may regulate lin- 5/gpr-1/gpr-2/goa-1 locally to create [...] | 0.771 |