STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sto-2Stomatin-2; May be involved in cilia-related function. (375 aa)    
Predicted Functional Partners:
ggr-1
Glycine receptor subunit beta-type 4; Glycine receptors are ligand-gated chloride channels. Channel opening is triggered by extracellular glycine. Contributes to the generation of inhibitory postsynaptic currents.
   
    0.544
R02E12.4
Uncharacterized protein.
   
  
 0.495
ift-139
Tetratricopeptide repeat protein 21 homolog; Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport. In particular, may act redundantly with the intraflagellar transport protein ift-43 to regulate the transport of specific ciliary cargo proteins such as che-3 which are related to motility. Functions in cilia biogenesis. Belongs to the TTC21 family.
   
    0.487
B0495.9
Uncharacterized protein B0495.9.
  
 
 0.465
bcs-1
BCS1 (Mitochondrial chaperone) homolog; Belongs to the AAA ATPase family.
  
 
 0.465
K08E7.6
Uncharacterized protein.
   
    0.465
ymel-1
ATP-dependent zinc metalloprotease YME1 homolog; ATP-dependent metalloprotease that catalyzes the degradation of folded and unfolded proteins with a suitable degron sequence in the mitochondrial intermembrane region (By similarity). Plays an important role in regulating mitochondrial morphology and function (By similarity); In the C-terminal section; belongs to the peptidase M41 family.
  
 
 0.465
Y108F1.1
annotation not available
  
 
 0.465
ppgn-1
AAA domain-containing protein.
  
 
 0.465
Y47C4A.1
Uncharacterized protein.
  
 
 0.465
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (26%) [HD]