node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
B0034.1 | best-13 | B0034.1.1 | F32B6.9.1 | Uncharacterized protein. | Bestrophin homolog 13; Forms chloride channels. | 0.697 |
B0034.1 | egl-26 | B0034.1.1 | C23H3.1a.1 | Uncharacterized protein. | LRAT domain-containing protein. | 0.660 |
best-13 | B0034.1 | F32B6.9.1 | B0034.1.1 | Bestrophin homolog 13; Forms chloride channels. | Uncharacterized protein. | 0.697 |
best-13 | bre-1 | F32B6.9.1 | C53B4.7b.1 | Bestrophin homolog 13; Forms chloride channels. | GDP-mannose 4,6 dehydratase 1; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. Involved in susceptibility to pore- forming crystal toxins in conjunction with bre-2, bre-3, bre-4, and bre-5. Involved in susceptibility to the nematotoxic C.cinerea galectin Cgl2, likely by contributing to the synthesis of N-glycans to which Cgl2 binds. Has a role in determining brood size. Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily. | 0.692 |
best-13 | clh-1 | F32B6.9.1 | T27D12.2a.1 | Bestrophin homolog 13; Forms chloride channels. | Chloride channel protein. | 0.469 |
best-13 | clh-3 | F32B6.9.1 | E04F6.11i.1 | Bestrophin homolog 13; Forms chloride channels. | Chloride channel protein clh-3; [Isoform a]: Voltage-gated chloride channel. Insensitive to depolarizing conditioning voltages, requires low voltages for activation, insensitive to chloride levels and has a mild sensitivity to low pH. Channel gating properties are conferred by the cytoplasmic C-terminus. Plays a role in egg laying by modulating hermaphrodite-specific neurons (HSN) excitability and the ovulatory contractions of gap-junction-coupled gonadal sheath cells. When active, may prevent tubular formation of the excretory canals. Activated during oocyte meiotic maturation and by [...] | 0.468 |
best-13 | clh-5 | F32B6.9.1 | C07H4.2.1 | Bestrophin homolog 13; Forms chloride channels. | Chloride channel protein. | 0.697 |
best-13 | clh-6 | F32B6.9.1 | R07B7.1.1 | Bestrophin homolog 13; Forms chloride channels. | Chloride channel protein. | 0.660 |
best-13 | dyf-18 | F32B6.9.1 | H01G02.2.1 | Bestrophin homolog 13; Forms chloride channels. | Protein kinase domain-containing protein. | 0.660 |
best-13 | egl-26 | F32B6.9.1 | C23H3.1a.1 | Bestrophin homolog 13; Forms chloride channels. | LRAT domain-containing protein. | 0.668 |
best-13 | mab-21 | F32B6.9.1 | F35G12.6.1 | Bestrophin homolog 13; Forms chloride channels. | Protein male abnormal 21; Acts in a cell autonomous fashion to specify the properties of the sensory ray and non-autonomously in the choice of hypodermal versus neuroblast cell fate. Belongs to the mab-21 family. | 0.436 |
best-13 | peli-1 | F32B6.9.1 | F25B4.2.1 | Bestrophin homolog 13; Forms chloride channels. | PELI1 and PELI2 related. | 0.692 |
bre-1 | best-13 | C53B4.7b.1 | F32B6.9.1 | GDP-mannose 4,6 dehydratase 1; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. Involved in susceptibility to pore- forming crystal toxins in conjunction with bre-2, bre-3, bre-4, and bre-5. Involved in susceptibility to the nematotoxic C.cinerea galectin Cgl2, likely by contributing to the synthesis of N-glycans to which Cgl2 binds. Has a role in determining brood size. Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily. | Bestrophin homolog 13; Forms chloride channels. | 0.692 |
bre-1 | dyf-18 | C53B4.7b.1 | H01G02.2.1 | GDP-mannose 4,6 dehydratase 1; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. Involved in susceptibility to pore- forming crystal toxins in conjunction with bre-2, bre-3, bre-4, and bre-5. Involved in susceptibility to the nematotoxic C.cinerea galectin Cgl2, likely by contributing to the synthesis of N-glycans to which Cgl2 binds. Has a role in determining brood size. Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily. | Protein kinase domain-containing protein. | 0.478 |
bre-1 | peli-1 | C53B4.7b.1 | F25B4.2.1 | GDP-mannose 4,6 dehydratase 1; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. Involved in susceptibility to pore- forming crystal toxins in conjunction with bre-2, bre-3, bre-4, and bre-5. Involved in susceptibility to the nematotoxic C.cinerea galectin Cgl2, likely by contributing to the synthesis of N-glycans to which Cgl2 binds. Has a role in determining brood size. Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily. | PELI1 and PELI2 related. | 0.612 |
clh-1 | best-13 | T27D12.2a.1 | F32B6.9.1 | Chloride channel protein. | Bestrophin homolog 13; Forms chloride channels. | 0.469 |
clh-1 | clh-3 | T27D12.2a.1 | E04F6.11i.1 | Chloride channel protein. | Chloride channel protein clh-3; [Isoform a]: Voltage-gated chloride channel. Insensitive to depolarizing conditioning voltages, requires low voltages for activation, insensitive to chloride levels and has a mild sensitivity to low pH. Channel gating properties are conferred by the cytoplasmic C-terminus. Plays a role in egg laying by modulating hermaphrodite-specific neurons (HSN) excitability and the ovulatory contractions of gap-junction-coupled gonadal sheath cells. When active, may prevent tubular formation of the excretory canals. Activated during oocyte meiotic maturation and by [...] | 0.517 |
clh-3 | best-13 | E04F6.11i.1 | F32B6.9.1 | Chloride channel protein clh-3; [Isoform a]: Voltage-gated chloride channel. Insensitive to depolarizing conditioning voltages, requires low voltages for activation, insensitive to chloride levels and has a mild sensitivity to low pH. Channel gating properties are conferred by the cytoplasmic C-terminus. Plays a role in egg laying by modulating hermaphrodite-specific neurons (HSN) excitability and the ovulatory contractions of gap-junction-coupled gonadal sheath cells. When active, may prevent tubular formation of the excretory canals. Activated during oocyte meiotic maturation and by [...] | Bestrophin homolog 13; Forms chloride channels. | 0.468 |
clh-3 | clh-1 | E04F6.11i.1 | T27D12.2a.1 | Chloride channel protein clh-3; [Isoform a]: Voltage-gated chloride channel. Insensitive to depolarizing conditioning voltages, requires low voltages for activation, insensitive to chloride levels and has a mild sensitivity to low pH. Channel gating properties are conferred by the cytoplasmic C-terminus. Plays a role in egg laying by modulating hermaphrodite-specific neurons (HSN) excitability and the ovulatory contractions of gap-junction-coupled gonadal sheath cells. When active, may prevent tubular formation of the excretory canals. Activated during oocyte meiotic maturation and by [...] | Chloride channel protein. | 0.517 |
clh-5 | best-13 | C07H4.2.1 | F32B6.9.1 | Chloride channel protein. | Bestrophin homolog 13; Forms chloride channels. | 0.697 |