node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
F43G6.5 | cfim-1 | F43G6.5.1 | F43G9.5.1 | Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. | Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] | 0.665 |
F43G6.5 | cpsf-1 | F43G6.5.1 | Y76B12C.7a.1 | Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. | Probable cleavage and polyadenylation specificity factor subunit 1; CPSF plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (By similarity). | 0.982 |
F43G6.5 | cpsf-2 | F43G6.5.1 | F09G2.4.1 | Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. | Probable cleavage and polyadenylation specificity factor subunit 2; CPSF plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition. | 0.945 |
F43G6.5 | cpsf-3 | F43G6.5.1 | Y67H2A.1.1 | Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. | Cleavage and Polyadenylation Specificity Factor. | 0.970 |
F43G6.5 | cpsf-4 | F43G6.5.1 | F11A10.8.2 | Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. | Cleavage and Polyadenylation Specificity Factor. | 0.958 |
F43G6.5 | fipp-1 | F43G6.5.1 | F32D1.9b.2 | Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. | Fip1 domain-containing protein. | 0.968 |
F43G6.5 | pfs-2 | F43G6.5.1 | R06A4.9a.1 | Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. | pre-mRNA 3' end processing protein pfs-2; Essential for both cleavage and polyadenylation of pre-mRNA 3' ends (By similarity). Involved in neuron development, probably by regulating pre-mRNA 3'-end processing. | 0.927 |
F43G6.5 | ssup-72 | F43G6.5.1 | T13C2.4.1 | Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. | RNA polymerase II subunit A C-terminal domain phosphatase ssup-72; Protein phosphatase that dephosphorylates 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the large RNA polymerase II subunit ama-1. By regulating the phosphorylation status of ama-1 and thus ama-1 binding to specific polyadenylation sites, regulates alternative polyadenylation of pre- mRNAs, including unc-44 and dlk-1 mRNAs. This results in the tissue-specific expression of unc-44 isoforms. | 0.842 |
F43G6.5 | suf-1 | F43G6.5.1 | F28C6.6.2 | Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. | Suf domain-containing protein. | 0.924 |
F43G6.5 | symk-1 | F43G6.5.1 | F25G6.2.1 | Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. | SYMpleKin cleavage and polyadenylation factor. | 0.991 |
cfim-1 | F43G6.5 | F43G9.5.1 | F43G6.5.1 | Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] | Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. | 0.665 |
cfim-1 | cpsf-1 | F43G9.5.1 | Y76B12C.7a.1 | Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] | Probable cleavage and polyadenylation specificity factor subunit 1; CPSF plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition. This subunit is involved in the RNA recognition step of the polyadenylation reaction (By similarity). | 0.834 |
cfim-1 | cpsf-2 | F43G9.5.1 | F09G2.4.1 | Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] | Probable cleavage and polyadenylation specificity factor subunit 2; CPSF plays a key role in pre-mRNA 3'-end formation, recognizing the AAUAAA signal sequence and interacting with poly(A)polymerase and other factors to bring about cleavage and poly(A) addition. | 0.832 |
cfim-1 | cpsf-3 | F43G9.5.1 | Y67H2A.1.1 | Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] | Cleavage and Polyadenylation Specificity Factor. | 0.844 |
cfim-1 | cpsf-4 | F43G9.5.1 | F11A10.8.2 | Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] | Cleavage and Polyadenylation Specificity Factor. | 0.946 |
cfim-1 | fipp-1 | F43G9.5.1 | F32D1.9b.2 | Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] | Fip1 domain-containing protein. | 0.970 |
cfim-1 | pfs-2 | F43G9.5.1 | R06A4.9a.1 | Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] | pre-mRNA 3' end processing protein pfs-2; Essential for both cleavage and polyadenylation of pre-mRNA 3' ends (By similarity). Involved in neuron development, probably by regulating pre-mRNA 3'-end processing. | 0.802 |
cfim-1 | ssup-72 | F43G9.5.1 | T13C2.4.1 | Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] | RNA polymerase II subunit A C-terminal domain phosphatase ssup-72; Protein phosphatase that dephosphorylates 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the large RNA polymerase II subunit ama-1. By regulating the phosphorylation status of ama-1 and thus ama-1 binding to specific polyadenylation sites, regulates alternative polyadenylation of pre- mRNAs, including unc-44 and dlk-1 mRNAs. This results in the tissue-specific expression of unc-44 isoforms. | 0.636 |
cfim-1 | suf-1 | F43G9.5.1 | F28C6.6.2 | Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] | Suf domain-containing protein. | 0.821 |
cfim-1 | symk-1 | F43G9.5.1 | F25G6.2.1 | Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] | SYMpleKin cleavage and polyadenylation factor. | 0.840 |