STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F32H5.4MFS domain-containing protein. (528 aa)    
Predicted Functional Partners:
F19F10.12
Beta-Casp domain-containing protein.
   
 
 0.763
ZC376.6
INTegrator complex Subunit homolog.
   
 
 0.750
F10B5.8
INTegrator complex Subunit homolog.
    
 
 0.738
Y92H12A.4
INTegrator complex Subunit homolog.
   
 
 0.737
D1043.1
INTegrator complex Subunit homolog.
    
 
 0.736
inst-1
INTegrator complex Subunit homolog.
    
 
 0.730
W04A4.5
INTegrator complex Subunit homolog.
    
 
 0.730
phf-30
PHD-type domain-containing protein.
    
 
 0.729
R02D3.4
INTegrator complex Subunit homolog.
    
 
 0.718
ama-1
DNA-directed RNA polymerase II subunit RPB1; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together with the second largest subunit. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB1 is part of the core element with the central large cl [...]
    
 
 0.687
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.