STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F33H1.3Uncharacterized protein F33H1.3. (359 aa)    
Predicted Functional Partners:
pqbp-1.1
WW domain-containing protein.
   
 0.955
cdc-5L
Cell Division Cycle related.
   
  0.916
plrg-1
WD_REPEATS_REGION domain-containing protein.
   
 0.904
cwc-15
Spliceosome-associated protein CWC15 homolog; Component of a spliceosomal complex that is required for activating pre-mRNA splicing.
   
  0.901
repo-1
Matrin-type domain-containing protein.
   
 
 0.863
M01E11.2
DUF1716 domain-containing protein.
   
  0.862
bcas-2
BCAS splicing factor homolog.
   
 
  0.814
prp-19
Pre-mRNA-processing factor 19; Probable ubiquitin-protein ligase which is mainly involved pre-mRNA splicing and DNA repair. Core component of the NTC/Nineteen complex which is part of the spliceosome and participates in its assembly, its remodeling and is required for its activity (By similarity). Together with emb-4, necessary for interaction of rnp-4, a probable exon junction complex component, with mRNAs and spliceosomal snRNAs. Plays a role in nuclear retention of unspliced mRNAs. Belongs to the WD repeat PRP19 family.
   
 
 0.811
hsp-1
Heat shock 70 kDa protein A.
   
 
  0.801
ubl-5
Ubiquitin-like protein 5.
    
   0.662
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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