STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F33H12.6ATP-dependent DNA helicase; Belongs to the helicase family. (1360 aa)    
Predicted Functional Partners:
C01G6.3
Uncharacterized protein.
      
 0.891
fbxc-55
F-box C protein.
      
 0.805
C25F9.4
SNF2_N domain-containing protein.
  
 
 0.786
C25F9.5
Uncharacterized protein.
  
 
 0.786
Y43F8B.14
SNF2_N domain-containing protein.
  
 
 0.786
F46G11.1
SF4 helicase domain-containing protein.
   
  
 0.769
M04C3.1
SNF2_N domain-containing protein.
  
 
 0.747
M04C3.2
SNF2_N domain-containing protein.
  
 
 0.729
let-765
Protein strawberry notch homolog; Transcriptional activator that functions upstream of the let- 60/Ras and let-23/EGFR signaling pathways to positively regulate lin-3 expression and thereby promote vulval induction. Plays a role in excretory duct development. Plays a role in male tail development.
      
 0.690
col-88
Col_cuticle_N domain-containing protein.
      
 0.664
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.