node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
F01F1.2 | coa-3 | F01F1.2.1 | F35D11.5.1 | COX assembly mitochondrial protein. | Coiled-coil_56 domain-containing protein. | 0.544 |
Y54F10AM.5 | coa-3 | Y54F10AM.5.1 | F35D11.5.1 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. | Coiled-coil_56 domain-containing protein. | 0.677 |
Y54F10AM.5 | cox-5A | Y54F10AM.5.1 | Y37D8A.14.1 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. | Cytochrome c oxidase subunit 5A, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...] | 0.989 |
Y54F10AM.5 | mrps-16 | Y54F10AM.5.1 | F56D1.3.1 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. | Probable 28S ribosomal protein S16, mitochondrial; Belongs to the bacterial ribosomal protein bS16 family. | 0.479 |
Y54F10AM.5 | tin-13 | Y54F10AM.5.1 | DY3.1.1 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. | Mitochondrial import inner membrane translocase subunit tim-13; Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The tim-8- tim-13 complex mediates the import of some pro [...] | 0.422 |
atad-3 | coa-3 | F54B3.3.1 | F35D11.5.1 | ATPase family AAA domain-containing protein 3; Essential for mitochondrial network organization, mitochondrial metabolism and cell growth at organism and cellular level. Important during development for the up-regulation of mitochondrial activity during the transition to higher larval stages. Regulates mitochondrial iron homeostasis. May play an important role in mitochondrial protein synthesis (By similarity). May also participate in mitochondrial DNA replication (By similarity). May bind to mitochondrial DNA D-loops and contribute to nucleoid stability (By similarity). Plays a role i [...] | Coiled-coil_56 domain-containing protein. | 0.517 |
coa-3 | F01F1.2 | F35D11.5.1 | F01F1.2.1 | Coiled-coil_56 domain-containing protein. | COX assembly mitochondrial protein. | 0.544 |
coa-3 | Y54F10AM.5 | F35D11.5.1 | Y54F10AM.5.1 | Coiled-coil_56 domain-containing protein. | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. | 0.677 |
coa-3 | atad-3 | F35D11.5.1 | F54B3.3.1 | Coiled-coil_56 domain-containing protein. | ATPase family AAA domain-containing protein 3; Essential for mitochondrial network organization, mitochondrial metabolism and cell growth at organism and cellular level. Important during development for the up-regulation of mitochondrial activity during the transition to higher larval stages. Regulates mitochondrial iron homeostasis. May play an important role in mitochondrial protein synthesis (By similarity). May also participate in mitochondrial DNA replication (By similarity). May bind to mitochondrial DNA D-loops and contribute to nucleoid stability (By similarity). Plays a role i [...] | 0.517 |
coa-3 | cox-10 | F35D11.5.1 | Y46G5A.2.1 | Coiled-coil_56 domain-containing protein. | Protoheme IX farnesyltransferase, mitochondrial; Converts protoheme IX and farnesyl diphosphate to heme O. Belongs to the ubiA prenyltransferase family. | 0.827 |
coa-3 | cox-15 | F35D11.5.1 | T06D8.5.1 | Coiled-coil_56 domain-containing protein. | Cytochrome OXidase assembly protein. | 0.866 |
coa-3 | cox-5A | F35D11.5.1 | Y37D8A.14.1 | Coiled-coil_56 domain-containing protein. | Cytochrome c oxidase subunit 5A, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...] | 0.522 |
coa-3 | lmtr-2 | F35D11.5.1 | Y97E10AR.7.2 | Coiled-coil_56 domain-containing protein. | Ragulator complex protein LAMTOR2 homolog; Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. May activate the TOR signaling cascade in response to amino acids; Belongs to the GAMAD family. | 0.513 |
coa-3 | mrps-16 | F35D11.5.1 | F56D1.3.1 | Coiled-coil_56 domain-containing protein. | Probable 28S ribosomal protein S16, mitochondrial; Belongs to the bacterial ribosomal protein bS16 family. | 0.502 |
coa-3 | taco-1 | F35D11.5.1 | Y50D7A.9.1 | Coiled-coil_56 domain-containing protein. | Translational Activator of Cytochrome c Oxidase. | 0.931 |
coa-3 | tin-13 | F35D11.5.1 | DY3.1.1 | Coiled-coil_56 domain-containing protein. | Mitochondrial import inner membrane translocase subunit tim-13; Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The tim-8- tim-13 complex mediates the import of some pro [...] | 0.504 |
cox-10 | coa-3 | Y46G5A.2.1 | F35D11.5.1 | Protoheme IX farnesyltransferase, mitochondrial; Converts protoheme IX and farnesyl diphosphate to heme O. Belongs to the ubiA prenyltransferase family. | Coiled-coil_56 domain-containing protein. | 0.827 |
cox-10 | cox-15 | Y46G5A.2.1 | T06D8.5.1 | Protoheme IX farnesyltransferase, mitochondrial; Converts protoheme IX and farnesyl diphosphate to heme O. Belongs to the ubiA prenyltransferase family. | Cytochrome OXidase assembly protein. | 0.999 |
cox-10 | cox-5A | Y46G5A.2.1 | Y37D8A.14.1 | Protoheme IX farnesyltransferase, mitochondrial; Converts protoheme IX and farnesyl diphosphate to heme O. Belongs to the ubiA prenyltransferase family. | Cytochrome c oxidase subunit 5A, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...] | 0.773 |
cox-10 | taco-1 | Y46G5A.2.1 | Y50D7A.9.1 | Protoheme IX farnesyltransferase, mitochondrial; Converts protoheme IX and farnesyl diphosphate to heme O. Belongs to the ubiA prenyltransferase family. | Translational Activator of Cytochrome c Oxidase. | 0.878 |