STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F35G12.7Uncharacterized protein. (115 aa)    
Predicted Functional Partners:
Y22D7AL.10
Uncharacterized protein; Belongs to the GroES chaperonin family.
     
 0.742
cutc-1
Copper homeostasis protein cutC homolog; Involved in copper homeostasis. Affects body morphology and length, egg laying and brood size; Belongs to the CutC family.
   
  
 0.676
rnh-2
Ribonuclease H2 subunit A; Catalytic subunit of RNase HII, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes (By similarity).
   
  
 0.587
atic-1
MGS domain-containing protein.
     
 0.559
phf-30
PHD-type domain-containing protein.
   
  
 0.559
C52B9.4
Uncharacterized protein.
      
 0.536
Y53F4B.21
Uncharacterized protein.
      
 0.529
cua-1
Copper transporting ATPase.
  
  
 0.512
F21D5.3
Plastocyanin-like domain-containing protein.
      
 0.473
F49E2.1
Cyclic pyranopterin monophosphate synthase; Isoform mocs1a and isoform mocs1b probably form a complex that catalyzes the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP). mocs1a catalyzes the cyclization of GTP to (8S)- 3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate and mocs1b catalyzes the subsequent conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'- triphosphate to cPMP; In the N-terminal section; belongs to the radical SAM superfamily. MoaA family.
     
 0.442
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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