STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
his-29Histone H2B 1. (122 aa)    
Predicted Functional Partners:
T01G1.4
Alkyl transferase; Belongs to the UPP synthase family.
      
 0.697
agt-2
AlkylGuanine DNA alkylTransferase.
      
 0.696
his-33
Histone H2A.
 
 
 
 0.597
his-30
Histone H2A.
 
 
 
 0.597
his-57
Histone H2A; Belongs to the histone H2A family.
 
 
 
 0.582
his-34
Histone H2B 1.
  
   
0.581
his-1
Histone H4.
 
 
 
 0.578
his-5
Histone H4.
 
 
 
 0.560
his-31
Histone H4.
 
 
 
 0.559
his-46
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
 
 
 
 0.558
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.