STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F35H10.5Uncharacterized protein. (79 aa)    
Predicted Functional Partners:
fnci-1
FANCI_HD2 domain-containing protein.
     
  0.900
fcd-2
FANCD2 (Fanconi's anemia defect) ortholog.
     
  0.900
Y48E1C.1
Uncharacterized protein.
    
  0.709
mxl-1
BHLH domain-containing protein.
   
    0.538
D2005.3
Uncharacterized protein D2005.3; Belongs to the PDCD5 family.
   
    0.456
ZK1127.12
Uncharacterized protein.
   
    0.455
emb-1
Anaphase-promoting complex subunit emb-1; Probable component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins (By similarity). Developmental role in early embryogenesis and the metaphase to anaphase transition in meiosis and mitosis. May be required for germline proliferation. Required for male tail development and hermaphrodite vulva formation.
   
    0.454
lsm-7
Sm domain-containing protein.
   
    0.422
gtf-2H5
General Transcription Factor homolog.
   
    0.418
C16C10.4
Probable histone deacetylase complex subunit SAP18; Acts in transcription repression. Involved in the tethering of the SIN3 complex to core histone proteins (By similarity). Belongs to the SAP18 family.
   
    0.410
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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