STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nhr-54Nuclear hormone receptor family member nhr-54; Orphan nuclear receptor; Belongs to the nuclear hormone receptor family. (422 aa)    
Predicted Functional Partners:
frpr-15
G_PROTEIN_RECEP_F1_2 domain-containing protein.
   
  
 0.881
Y75B12B.3
Uncharacterized protein.
      
 0.881
F09F7.5
CRIB domain-containing protein.
   
    0.846
T21C9.11
Uncharacterized protein.
   
    0.846
F11C1.4
Uncharacterized protein.
   
    0.829
C24B5.1
G_PROTEIN_RECEP_F1_2 domain-containing protein.
   
  
 0.809
dyf-5
Serine/threonine-protein kinase dyf-5; Serine/threonine-protein kinase which is required for ciliogenesis. Regulates the length and the morphology of sensory neuron cilia. In addition, plays a role in the anterograde intraflagellar transport (IFT) in the cilia by regulating the undocking of kinesin-II motor complex (composed of klp-11, klp-20 and kap-1) before reaching the distal segment and the docking of kinesin motor osm-3 onto IFT cargos; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. RCK subfamily.
   
   0.804
fbxa-199
G_PROTEIN_RECEP_F1_2 domain-containing protein.
   
    0.764
C17H11.1
G_PROTEIN_RECEP_F1_2 domain-containing protein.
      
 0.759
str-253
Seven TM Receptor.
   
    0.720
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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