node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C07A12.7 | rbf-1 | C07A12.7a.1 | F37A4.7d.1 | GAT domain-containing protein. | Rabphilin-1; Rab-3 effector. | 0.660 |
aex-6 | rab-3 | Y87G2A.4.1 | C18A3.6a.1 | Rab27. | Ras-related protein Rab-3; Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal (By similarity). Plays a role in the recruitment of endophilin unc-57 to synaptic vesicles. Probably by controlling dense-core vesicle trafficking, plays a role in the AVG neuron-mediated formation of the right axon tract of the ventral nerve cord. Belongs to the small GTPase superfamily. Rab family. | 0.511 |
aex-6 | rbf-1 | Y87G2A.4.1 | F37A4.7d.1 | Rab27. | Rabphilin-1; Rab-3 effector. | 0.899 |
lin-35 | lin-52 | C32F10.2.1 | ZK632.13a.1 | Retinoblastoma-like protein homolog lin-35; Key regulator of cell division which acts as a transcriptional repressor and negatively regulates cell cycle progression in its active unphosphorylated form, but allows cell cycle progression when phosphorylated. When unphosphorylated and in its active form, interacts with E2F transcription factors such as efl-1 to repress their transcriptional activity and negatively regulate the progression through the G1 phase of the cell cycle during postembryonic development. May furthermore act with cell cycle regulator cki-1 to negatively regulate cell [...] | Protein lin-52; Synthetic multivulva class B (synMuvB) protein. SynMuvB proteins are required to repress the induction of vulval development by Ras signaling and probably act by forming the multiprotein DRM complex that represses transcription. In association with the zinc finger protein ztf-11, negatively regulates the expression of non-neuronal genes during neurogenesis. Belongs to the lin-52 family. | 0.997 |
lin-35 | rbf-1 | C32F10.2.1 | F37A4.7d.1 | Retinoblastoma-like protein homolog lin-35; Key regulator of cell division which acts as a transcriptional repressor and negatively regulates cell cycle progression in its active unphosphorylated form, but allows cell cycle progression when phosphorylated. When unphosphorylated and in its active form, interacts with E2F transcription factors such as efl-1 to repress their transcriptional activity and negatively regulate the progression through the G1 phase of the cell cycle during postembryonic development. May furthermore act with cell cycle regulator cki-1 to negatively regulate cell [...] | Rabphilin-1; Rab-3 effector. | 0.698 |
lin-52 | lin-35 | ZK632.13a.1 | C32F10.2.1 | Protein lin-52; Synthetic multivulva class B (synMuvB) protein. SynMuvB proteins are required to repress the induction of vulval development by Ras signaling and probably act by forming the multiprotein DRM complex that represses transcription. In association with the zinc finger protein ztf-11, negatively regulates the expression of non-neuronal genes during neurogenesis. Belongs to the lin-52 family. | Retinoblastoma-like protein homolog lin-35; Key regulator of cell division which acts as a transcriptional repressor and negatively regulates cell cycle progression in its active unphosphorylated form, but allows cell cycle progression when phosphorylated. When unphosphorylated and in its active form, interacts with E2F transcription factors such as efl-1 to repress their transcriptional activity and negatively regulate the progression through the G1 phase of the cell cycle during postembryonic development. May furthermore act with cell cycle regulator cki-1 to negatively regulate cell [...] | 0.997 |
lin-52 | rbf-1 | ZK632.13a.1 | F37A4.7d.1 | Protein lin-52; Synthetic multivulva class B (synMuvB) protein. SynMuvB proteins are required to repress the induction of vulval development by Ras signaling and probably act by forming the multiprotein DRM complex that represses transcription. In association with the zinc finger protein ztf-11, negatively regulates the expression of non-neuronal genes during neurogenesis. Belongs to the lin-52 family. | Rabphilin-1; Rab-3 effector. | 0.838 |
mrpl-22 | mrpl-39 | Y39A1A.6.1 | Y46H3A.7a.1 | Mitochondrial Ribosomal Protein, Large; Belongs to the universal ribosomal protein uL22 family. | Mitochondrial Ribosomal Protein, Large. | 0.989 |
mrpl-22 | rbf-1 | Y39A1A.6.1 | F37A4.7d.1 | Mitochondrial Ribosomal Protein, Large; Belongs to the universal ribosomal protein uL22 family. | Rabphilin-1; Rab-3 effector. | 0.699 |
mrpl-39 | mrpl-22 | Y46H3A.7a.1 | Y39A1A.6.1 | Mitochondrial Ribosomal Protein, Large. | Mitochondrial Ribosomal Protein, Large; Belongs to the universal ribosomal protein uL22 family. | 0.989 |
mrpl-39 | rbf-1 | Y46H3A.7a.1 | F37A4.7d.1 | Mitochondrial Ribosomal Protein, Large. | Rabphilin-1; Rab-3 effector. | 0.700 |
prmt-6 | rbf-1 | C23H5.1.1 | F37A4.7d.1 | Methyltransf_25 domain-containing protein. | Rabphilin-1; Rab-3 effector. | 0.704 |
rab-3 | aex-6 | C18A3.6a.1 | Y87G2A.4.1 | Ras-related protein Rab-3; Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal (By similarity). Plays a role in the recruitment of endophilin unc-57 to synaptic vesicles. Probably by controlling dense-core vesicle trafficking, plays a role in the AVG neuron-mediated formation of the right axon tract of the ventral nerve cord. Belongs to the small GTPase superfamily. Rab family. | Rab27. | 0.511 |
rab-3 | rbf-1 | C18A3.6a.1 | F37A4.7d.1 | Ras-related protein Rab-3; Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal (By similarity). Plays a role in the recruitment of endophilin unc-57 to synaptic vesicles. Probably by controlling dense-core vesicle trafficking, plays a role in the AVG neuron-mediated formation of the right axon tract of the ventral nerve cord. Belongs to the small GTPase superfamily. Rab family. | Rabphilin-1; Rab-3 effector. | 0.939 |
rab-3 | ric-4 | C18A3.6a.1 | Y22F5A.3b.1 | Ras-related protein Rab-3; Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal (By similarity). Plays a role in the recruitment of endophilin unc-57 to synaptic vesicles. Probably by controlling dense-core vesicle trafficking, plays a role in the AVG neuron-mediated formation of the right axon tract of the ventral nerve cord. Belongs to the small GTPase superfamily. Rab family. | Synaptosomal-associated protein; Belongs to the SNAP-25 family. | 0.888 |
rbf-1 | C07A12.7 | F37A4.7d.1 | C07A12.7a.1 | Rabphilin-1; Rab-3 effector. | GAT domain-containing protein. | 0.660 |
rbf-1 | aex-6 | F37A4.7d.1 | Y87G2A.4.1 | Rabphilin-1; Rab-3 effector. | Rab27. | 0.899 |
rbf-1 | lin-35 | F37A4.7d.1 | C32F10.2.1 | Rabphilin-1; Rab-3 effector. | Retinoblastoma-like protein homolog lin-35; Key regulator of cell division which acts as a transcriptional repressor and negatively regulates cell cycle progression in its active unphosphorylated form, but allows cell cycle progression when phosphorylated. When unphosphorylated and in its active form, interacts with E2F transcription factors such as efl-1 to repress their transcriptional activity and negatively regulate the progression through the G1 phase of the cell cycle during postembryonic development. May furthermore act with cell cycle regulator cki-1 to negatively regulate cell [...] | 0.698 |
rbf-1 | lin-52 | F37A4.7d.1 | ZK632.13a.1 | Rabphilin-1; Rab-3 effector. | Protein lin-52; Synthetic multivulva class B (synMuvB) protein. SynMuvB proteins are required to repress the induction of vulval development by Ras signaling and probably act by forming the multiprotein DRM complex that represses transcription. In association with the zinc finger protein ztf-11, negatively regulates the expression of non-neuronal genes during neurogenesis. Belongs to the lin-52 family. | 0.838 |
rbf-1 | mrpl-22 | F37A4.7d.1 | Y39A1A.6.1 | Rabphilin-1; Rab-3 effector. | Mitochondrial Ribosomal Protein, Large; Belongs to the universal ribosomal protein uL22 family. | 0.699 |