node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
F41G3.6 | bath-41 | F41G3.6.1 | F37A4.9.1 | Uncharacterized protein. | BTB and MATH domain-containing protein 41; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | 0.579 |
F52C6.3 | bath-41 | F52C6.3.1 | F37A4.9.1 | Ubiquitin-like domain-containing protein. | BTB and MATH domain-containing protein 41; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | 0.554 |
F52C6.3 | bath-42 | F52C6.3.1 | C50C3.8.1 | Ubiquitin-like domain-containing protein. | BTB and MATH domain-containing protein 42; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | 0.554 |
F52C6.3 | bath-44 | F52C6.3.1 | C07D10.2b.2 | Ubiquitin-like domain-containing protein. | BTB and MATH domain containing. | 0.551 |
F52C6.3 | cul-3 | F52C6.3.1 | Y108G3AL.1a.3 | Ubiquitin-like domain-containing protein. | Cullin-3; Probable core component of multiple cullin-RING-based BCB (BTB-CUL3-BTB) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Probably acts as a scaffold protein which may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Required to target mei-3/katanin for degradation at the meiosis to mitosis transition via its neddylation and deneddylation. Functions in ubiquitin-mediated degradation of CKIs to target cki-1 for degradation. Regulates microtubule st [...] | 0.678 |
F52C6.3 | mel-26 | F52C6.3.1 | ZK858.4b.1 | Ubiquitin-like domain-containing protein. | Protein maternal effect lethal 26; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Controls degradation of microtubule severing protein mei-1 after meiosis. Controls degradation of ppfr-1, the regulatory subunit of PP4 complex, after meiosis. In body wall muscles, involved in the organization of myosin thick filaments, likely by regulating the degradation of mei-1 downstream of unc-89. May also activate the TORC1 pathway. | 0.555 |
F52C6.3 | psmd-9 | F52C6.3.1 | C44B7.1.1 | Ubiquitin-like domain-containing protein. | Probable 26S proteasome non-ATPase regulatory subunit 9; Acts as a chaperone during the assembly of the 26S proteasome, specifically of the base subcomplex of the 19S regulatory complex (RC); Belongs to the proteasome subunit p27 family. | 0.544 |
F52C6.3 | rbx-1 | F52C6.3.1 | ZK287.5.2 | Ubiquitin-like domain-containing protein. | RING-box protein 1; Component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate (By similarity). Essential for meiosis, mitotic chromosomal condensation and cytokinesis. Involved in histone H3 phosphorylation. | 0.765 |
F52C6.3 | ubq-1 | F52C6.3.1 | F25B5.4a.2 | Ubiquitin-like domain-containing protein. | Ubiquitin-related; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-48-linked is involved in protein degrad [...] | 0.486 |
M02B7.7 | bath-41 | M02B7.7.1 | F37A4.9.1 | Uncharacterized protein. | BTB and MATH domain-containing protein 41; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | 0.638 |
M02B7.7 | bath-42 | M02B7.7.1 | C50C3.8.1 | Uncharacterized protein. | BTB and MATH domain-containing protein 42; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | 0.647 |
M02B7.7 | bath-44 | M02B7.7.1 | C07D10.2b.2 | Uncharacterized protein. | BTB and MATH domain containing. | 0.643 |
M02B7.7 | mel-26 | M02B7.7.1 | ZK858.4b.1 | Uncharacterized protein. | Protein maternal effect lethal 26; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Controls degradation of microtubule severing protein mei-1 after meiosis. Controls degradation of ppfr-1, the regulatory subunit of PP4 complex, after meiosis. In body wall muscles, involved in the organization of myosin thick filaments, likely by regulating the degradation of mei-1 downstream of unc-89. May also activate the TORC1 pathway. | 0.767 |
bath-41 | F41G3.6 | F37A4.9.1 | F41G3.6.1 | BTB and MATH domain-containing protein 41; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | Uncharacterized protein. | 0.579 |
bath-41 | F52C6.3 | F37A4.9.1 | F52C6.3.1 | BTB and MATH domain-containing protein 41; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | Ubiquitin-like domain-containing protein. | 0.554 |
bath-41 | M02B7.7 | F37A4.9.1 | M02B7.7.1 | BTB and MATH domain-containing protein 41; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | Uncharacterized protein. | 0.638 |
bath-41 | bath-42 | F37A4.9.1 | C50C3.8.1 | BTB and MATH domain-containing protein 41; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | BTB and MATH domain-containing protein 42; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | 0.552 |
bath-41 | bath-44 | F37A4.9.1 | C07D10.2b.2 | BTB and MATH domain-containing protein 41; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | BTB and MATH domain containing. | 0.614 |
bath-41 | cul-3 | F37A4.9.1 | Y108G3AL.1a.3 | BTB and MATH domain-containing protein 41; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | Cullin-3; Probable core component of multiple cullin-RING-based BCB (BTB-CUL3-BTB) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. Probably acts as a scaffold protein which may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. Required to target mei-3/katanin for degradation at the meiosis to mitosis transition via its neddylation and deneddylation. Functions in ubiquitin-mediated degradation of CKIs to target cki-1 for degradation. Regulates microtubule st [...] | 0.811 |
bath-41 | mel-26 | F37A4.9.1 | ZK858.4b.1 | BTB and MATH domain-containing protein 41; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | Protein maternal effect lethal 26; Probable substrate-specific adapter of an E3 ubiquitin- protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Controls degradation of microtubule severing protein mei-1 after meiosis. Controls degradation of ppfr-1, the regulatory subunit of PP4 complex, after meiosis. In body wall muscles, involved in the organization of myosin thick filaments, likely by regulating the degradation of mei-1 downstream of unc-89. May also activate the TORC1 pathway. | 0.556 |