STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
F37A8.5Protein yippee-like F37A8.5; Belongs to the yippee family. (137 aa)    
Predicted Functional Partners:
Y54E5A.7
Uncharacterized protein.
   
 
 0.668
Y39H10A.6
WD_REPEATS_REGION domain-containing protein.
   
 
 0.663
T07D1.2
Zf-RING_UBOX domain-containing protein.
   
 
 0.613
tag-304
Uncharacterized protein.
   
 
 0.493
sqst-2
ZZ-type domain-containing protein.
   
   0.460
memo-1
Protein memo-1 homolog; Plays a role in the oxidative stress response and the maintenance of longevity by regulating the interaction between GTPase rho-1 and oxidase bli-3. In turn, this serves to modulate bli-3 activity and the control of reactive oxygen species production. May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton (By similarity); Belongs to the MEMO1 family.
   
  
 0.434
fbxl-1
F-box/LRR-repeat protein fbxl-1; Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex (By similarity). Plays a role in regulating the entry into the dauer state. In hermaphrodites, may play a role in modulating the rate of defecation.
   
 
 0.425
maea-1
MAEA (MAcrophage Erythroblast Attacher protein) homolog.
   
 
 0.407
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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