STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lir-3Transcription factor lir-3; Positively regulates the RNA polymerase III-associated transcription of small non-coding RNAs. (284 aa)    
Predicted Functional Partners:
moag-4
Modifier of protein aggregation 4; Positive regulator of protein aggregation and age-related proteotoxicity. Induces conformational changes in aggregation-prone proteins, driving them into compact formations preceding the formation of aggregates.
      
 0.852
rps-21
40S ribosomal protein S21.
      
 0.698
npp-3
Nuclear Pore complex Protein.
      
 0.697
snpc-4
snRNA-activating protein complex subunit 4 homolog; Binds to the promoter regions of RNA polymerase II and III small-nuclear RNA genes, type 3 RNA polymerase III non-coding RNA genes, small nucleolar RNAs and transfer RNA genes. Required for expression of mature 21U-RNAs.
      
 0.549
hog-1
HOG only (Hedgehog Hog domain alone).
      
 0.533
npp-13
Nuclear pore protein.
      
 0.533
B0001.7
Uncharacterized protein.
    
   0.420
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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