STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
col-81Col_cuticle_N domain-containing protein. (306 aa)    
Predicted Functional Partners:
col-139
Col_cuticle_N domain-containing protein.
   
  
0.999
col-129
Col_cuticle_N domain-containing protein.
  
  
0.999
perm-4
PERMeable eggshell.
   
  
 0.719
cyp-34A1
CYtochrome P450 family; Belongs to the cytochrome P450 family.
    
 
 0.708
cyp-13B1
Putative cytochrome P450 cyp-13B1; Cytochromes P450 are a group of heme-thiolate monooxygenases (Probable). They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics (Probable). May play a role in the regulation of lifespan.
    
 
 0.706
cyp-31A2
CYtochrome P450 family; Belongs to the cytochrome P450 family.
   
 
 0.689
coq-8
Atypical kinase coq-8, mitochondrial; Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration. Its substrate specificity is unclear: either acts as protein kinase that phosphorylates other proteins in the CoQ complex to stabilize their interactions or acts as a small molecule kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway.
      
 0.663
col-106
Col_cuticle_N domain-containing protein.
  
   0.661
asg-2
Probable ATP synthase subunit g 2, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism [...]
      
 0.660
col-124
Col_cuticle_N domain-containing protein.
  
   
0.625
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.