STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ram-2Col_cuticle_N domain-containing protein. (306 aa)    
Predicted Functional Partners:
fntb-1
Protein farnesyltransferase subunit beta; Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins. The beta subunit is responsible for peptide-binding.
      
 0.741
lon-8
Protein lon-8; Secreted protein that is involved in larval elongation, early adult growth and male tail development.
   
  
 0.729
ram-5
ZP domain-containing protein.
   
  
 0.676
col-107
Col_cuticle_N domain-containing protein.
   
   
0.629
col-125
Col_cuticle_N domain-containing protein.
   
   
0.615
adt-1
A disintegrin and metalloproteinase with thrombospondin motifs adt-1; Plays a role in ray morphogenesis in the male tail, probably by remodeling the extracellular matrix (ECM) in the cuticle.
   
 
 0.595
col-10
Cuticle collagen 10; Nematode cuticles are composed largely of collagen-like proteins. The cuticle functions both as an exoskeleton and as a barrier to protect the worm from its environment (By similarity).
   
   
0.592
col-130
Col_cuticle_N domain-containing protein.
   
    0.592
col-167
Col_cuticle_N domain-containing protein.
   
   
0.592
ZK180.5
Uncharacterized protein.
   
   0.590
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Rhabditis elegans, roundworm
Server load: low (26%) [HD]